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Stuart MacNeill

The Eukaryotic Replisome: a Guide to Protein Structure and Function

gebondenEngels9789400745711 24-8-2012

High-fidelity chromosomal DNA replication underpins all life on the planet. In humans, there are clear links between chromosome replication defects and genome instability, genetic disease and cancer, making a detailed understanding of the molecular mechanisms of genome duplication vital for future advances in diagnosis and treatment. Meer

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Natural compounds as inducers of cell death

gebondenEngels9789400745742 1-9-2012

Cancer still remains a most important killer and even though synthetic chemotherapeutic agents are currently used, they are cost-intensive and do not always meet the expectations. Meer

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The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications

gebondenEngels9789400745803 28-11-2012

Angiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis. Meer

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S. Campbell

The Management of the Menopause & Post-Menopausal Years

paperbackEngels9789401161671 18-5-2012

Despite the fact that the average woman spends one third of her life after the menopause, medical research has been devoted almost entirely to the repro ductive period of her life span. Meer

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Hans J. Eysenck

The Measurement of Personality

paperbackEngels9789401161701 12-2-2012

This book deals with the measurement of personality, in detail concerning the philosophical discussions of this much the same way as an earlier book dealt with the concept; the reader must be referred to Suppe's (1974) measurement of intelligence (Eysenck, 1973). Meer

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D.N. Raine

Medico-Social Management of Inherited Metabolic Disease

paperbackEngels9789401161756 12-3-2012

The study of inherited metabolic disease became a subject of more than academic interest in 1953 when Bickel, Gerrard and Hickmans dis covered that the totally disabling consequences of phenylketonuria could be prevented if treatment was instituted in the first months of life. Meer

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DNA Repair of Cancer Stem Cells

gebondenEngels9789400745896 27-7-2012

The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. Meer

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Drug Transporters in Drug Disposition, Effects and Toxicity

gebondenEngels9789811376467 11-10-2019

This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Meer

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Drug Transporters in Drug Disposition, Effects and Toxicity

paperbackEngels9789811376498 12-10-2020

This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Meer

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J. Marks

The Benzodiazepines

paperbackEngels9789401162050 23-2-2012

The story of the benzodiazepines is a fascinating one: the synthesis of a long series of inert compounds and the abandonment of the project: months later, the renewal of the project and the discovery that this compound R05-0690 (Librium ®) was a sedative and muscle relaxant in laboratory animals: the recognition that its postulated structure was wrong and that it was in fact a member of an entirely new chemical class: the excitement caused by the discovery of the powerful taming effect of the drug in wild animals: the even greater excitement in medical circles when its dramatic anxiety relieving effects were cstablished in humans: the subsequent enormous world wide usc of drugs of the benzodiazepine group. Meer

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The Biological Basis of Schizophrenia

paperbackEngels9789401162081 3-4-2012

For years lip service has been paid to a belief in a biological basis for schizophrenia, but ,nevertheless psychosocial and psychodynamic "theories" of schizophrenia have been promulgated, and these have detracted from the all important biological work, Eclecticism has ruled the day and has caused considerable confusion, As a result research in schizophrenia has not progressed as fast as it should have done and treatment has been less effective than it could otherwise have been. Meer

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Robert Alan Prentky

The Biological Aspects of Normal Personality

paperbackEngels9789401162166 17-3-2012

It is the mission of this volume to accomplish functioning normally. Similarly, if our MMPI two goals: (1) present a relatively broad profile falls entirely within the designated spectrum or research focusing on biophysical 'normal range' we conclude that our person aspects of personality, (2) select those studies ality is functioning normally. Meer

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M.H. Lessof

Immunological and Clinical Aspects of Allergy

paperbackEngels9789401162197 18-2-2012

In the scientific aspects of immunology, the pace of advance has been almost overwhelming, but with some notable exceptions, clinical benefits have been slow. Meer

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M.J. Denham

The Treatment of Medical Problems in the Elderly

paperbackEngels9789401162258 21-4-2014

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The Premenstrual Syndrome

paperbackEngels9789401162579 12-2-2012

Despite a plethora of theories, premenstrual syndrome (PMS) has remained an enigma. There has persisted in the literature a constant conflict as to the existence of the syndrome, a question as to whether it is one syndrome or several, and a debate as to whether the origin is psychic, somatic, or both. Meer

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W.S. Bullough

The Dynamic Body Tissues

paperbackEngels9789401162630 12-2-2012

The study of life is the study of tier upon tier of interlocking homeostatic mechanisms, and the main theme of this book concerns that part of the system that ensures cellular and tissue homeostasis and thus maintains tissue mass, tissue structure and tissue function in the adult mammal. Meer

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R.W. Stout

Hormones and Atherosclerosis

paperbackEngels9789401162661 12-2-2012

As the acute infectious diseases recede in importance, and as the number of people surviving into middle and old age increases, the chronic 'degenerative' diseases assume greater importance as causes of death and disability. Meer

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D.R. Pegg

Organ Preservation

paperbackEngels9789401162692 17-2-2012

During the past 10 years, there have been many international meetings on the storage of organs prior to transplantation, and several have led to the publication of proceedings; there have also been a number of other books on this subject-. Meer

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D. Bovill

Tutorial Therapy

paperbackEngels9789401162722 23-2-2012

Dr Bovill is a remarkable person and this book is an eloquent expression of remarkable achievement. When, some seven years ago, I came to the North West from the relative psychotherapeutic luxury of London, I was amazed to discover a busy whole-time general psychiatrist who claimed that she and her staff were giving a comprehensive service for the treatment of psycho neurosis by psychological means. Meer

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P. Carrick

Medical Ethics in Antiquity

gebondenEngels9789027718259 31-3-1985

The idea of reviewing the ethical concerns of ancient medicine with an eye as to how they might instruct us about the extremely lively disputes of our own contemporary medicine is such a natural one that it surprises us to real ize how very slow we have been to pursue it in a sustained way_ Ideologues have often seized on the very name of Hippocrates to close off debate about such matters as abortion and euthanasia - as if by appeal to a well-known and sacred authority that no informed person would care or dare to oppose_ And yet, beneath the polite fakery of such reference, we have deprived our selves of a familiarity with the genuinely 'unsimple' variety of Greek and Roman reflections on the great questions of medical ethics. Meer

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