Section I: Orthotopic And Heterotopic Heart Transplantation.- 1 Experimental development and early clinical experience.- 2 Indications, selection and management of the recipient.- 3 The concept and diagnosis of brain death.- 4 Medico-legal aspects.- 5 Donor organ availability and transplant coordination.- 6 Selection and management of the donor.- 7 Storage of the donor heart.- 8 Pretransplant immunological considerations.- 9 Anesthetic management including cardiopulmonary bypass.- 10 Surgical technique of orthotopic heart transplantation.- 11 Surgical technique of heterotopic heart transplantation.- 12 Immediate postoperative care and maintenance immunosuppressive therapy.- 13 Physiology and pharmacology of the transplanted heart.- 14 Immunobiology of allograft destruction.- 15 Pathology of acute rejection.- 16 Diagnosis and management of acute rejection.- 17 Infectious complications.- 18 Pathology of graft atherosclerosis (chronic rejection).- 19 Diagnosis and management of graft atherosclerosis (chronic rejection).- 20 Retransplantation.- 21 Malignant neoplasia in the immunocompromised patient.- 22 Other complications of transplantation and immunosuppressive therapy.- 23 Heterotopic heart transplantation — indications and special considerations.- 24 Heart transplantation in infants and children — indications and special considerations.- 25 Psychiatric aspects.- 26 Medico-social aspects.- 27 Nutrition and diet.- 28 Exercise rehabilitation.- 29 Non-cardiac surgery in patients with heart transplants — anesthetic and operative considerations.- 30 Non-cardiac autopsy findings in patients with heart (or heart—lung) transplants.- 31 Results of cardiac transplantation and factors influencing survival. 1. International Society for Heart Transplantation Registry.- 32 Results of cardiac transplantation and factors influencing survival. 2. Collaborative Heart Transplant Study.- Section II: Transplantation Of The Heart And Both Lungs.- 33 Experimental background and early clinical experience.- 34 Indications, selection, and management of the recipient.- 35 Selection of the donor; excision and storage of donor organs.- 36 Anesthetic management.- 37 Surgical technique of the recipient operation.- 38 Postoperative management, surgical complications, diagnosis and management of acute rejection.- 39 Immunological aspects.- 40 Pathology of heart—lung transplantation.- 41 Infectious complications.- 42 Physiology and pharmacology of the transplanted lungs.- 43 Diagnosis and management of bronchiolitis obliterans (chronic rejection): retransplantation.- 44 Results of heart—lung transplantation and factors influencing survival.- Section III: Single And Double Lung Transplantation.- 45 Experimental background and early clinical experience.- 46 Indications, selection and management of the recipient.- 46 Selection of the donor: excision and storage of the lungs.- 48 Anesthesia for single lung transplantation.- 49 Surgical technique of single lung transplantation.- 50 Surgical technique of double lung transplantation.- 51 Postoperative management.- 53 Complications.- 54 Results of lung transplantation.- Section IV: The Role Of Mechanical Support Devices In Cardiac Transplantation.- 54 Indications and selection of cardiac support device.- 55 Non-pulsatile centrifugal pumps.- 56 Pulsatile ventricular assist devices.- 57 Total artificial hearts.- 58 Results of mechanical circulatory support as a ‘bridge’ to cardiac transplantation — Combined Registry Report.- Section V: Permanent Cardiac Replacement By The Total Artificial Heart.- 59 Experimental background and current problems.- 60 Clinical experience.- Section VI: Cardiac Xenotransplantation.- 61 Xenotransplantation: overview.- 62 Pathology of xenograft rejection.- 63 Mechanisms and possible management of hyperacute (vascular, humoral) or xenograft rejection.- 64 Clinical experience.- Section VII: Cardiac Augmentation With Skeletal Muscle.- 65 Cardiomyoplasty.- 66 Blood pumps constructed from skeletal muscle.- Section VIII: The Future Of Thoracic Organ Replacement.- 67 Some ethical and logistic issues in transplantation.- 68 Heart and lung replacement: future perspectives.
