, ,

Neuroprotection and Neuroregeneration for Retinal Diseases

Specificaties
Gebonden, 356 blz. | Engels
Springer Japan | 2014e druk, 2014
ISBN13: 9784431549642
Rubricering
Springer Japan 2014e druk, 2014 9784431549642
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa. Glaucoma is one of the main causes of blindness throughout the world, and other diseases such as AMD and retinitis pigmentosa also lead to loss of vision. All these conditions are characterized by degeneration of specific retinal cell types, making it essential to establish treatments to protect retinal neurons and the optic nerve.

With that aim in mind, this book explains the mechanisms underlying aforementioned diseases and their experimental models. The novel strategy proposals for the treatment of retinal diseases based on the concept of neuroprotection are also discussed in the main body of the text, while the section on regenerative research discusses optic nerve regeneration, endothelial progenitor cells, and iPS cells.

This book is recommended as a professional reference work for all doctors and trainees in the field of ophthalmology who are interested in neuroprotective and neuroregenerative treatments.

Specificaties

ISBN13:9784431549642
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:356
Uitgever:Springer Japan
Druk:2014

Inhoudsopgave

<p>Part I Neuroprotection for Glaucoma.- 1. Molecular Architecture of Glutamate Signaling Pathway in Glaucomatous Optic Neuropathy.- 2. Calcium and Calpain Activation.- 3. Classical Signaling Pathways.- 4. Antioxidative Treatment for Neuroprotection in Glaucoma.- 5. ER stress.- 6. Nitric Oxide Contributes to Retinal Ganglion Cell Survival Through Protein S-Nitrosylation after Optic Nerve Injury.- 7. Neurotrophic factors.- 8. RIP Kinase-Mediated Programmed Necrosis.- 9. Axonal Degeneration.- 10. Axonal Transport.- 11. Interaction Between RGC Bodies and Glia.- 12. Aquaporin in optic neuropathies.- 13. Microglia.- Part II Neuroprotection for Age-Related Macular Degeneration (AMD), Retinal Pigmentary Degeneration.- 14. Neuroprotection for Photoreceptors.- 15. Retinal Photooxidative Stress and Its Modifiers.- 16. Roles of the Retinal Pigment Epithelium in Neuroprotection.- 17. Oxidative Stress in the RPE and Its Contribution to AMD Pathogenesis; Implication of Light Exposure.- 18. Interaction Between Photoreceptors and RPEs.- Part III Neuroprotection for Other Retinal Diseases.- 19. Neuroprotection for Retinal Detachment.- 20. Neuroinflammation.- 21. Optic Neuritis.- 22. Neuroprotection by Endothelial Progenitor Cells for Retinal Degeneration.- 23. Optic Nerve Regeneration.</p>

Rubrieken

    Personen

      Trefwoorden

        Neuroprotection and Neuroregeneration for Retinal Diseases