Brain Edema XII

General review.- Concept and pathogenesis of “hypoxic-ischemic encephalopathy”.- Pathophysiology of traumatic brain edema : current concepts.- Brain edema from intracerebral hemorrhage.- Hydrostatic brain edema: basic mechanisms and clinical aspect.- Non-invasive imaging methods for the characterization of the pathophysiology of brain ischemia.- Cécile & Oskar Vogt: The significance of their contributions in modern neuroscience.- Imaging.- Estimating blood-brain barrier opening in a rat model of hemorrhagic transformation with Patlak plots of Gd-DTPA contrast-enhanced MRI.- Recent development of MR imaging technique for the investigation of brain function.- Energy metabolism and cerebral blood flow during cytotoxic brain edema induced by 6-aminonicotinamide.- PET neuroreceptor imaging as predictor of severe cerebral ischemic insult.- Pet investigation of post-traumatic cerebral blood volume and blood flow.- Quantitative evaluation of cerebral vascular permeability using multi-slice dynamic CT.- Acetazolamide vasoreactivity evaluated by transcranial harmonic perfusion imaging: relationship with transcranial Doppler sonography and dynamic CT.- Functional brain imaging of optical topography.- Experimental global ischemia.- Significant shrinkage of extracellular space during global cerebral ischemia: differences in gray and white matter ischemia.- NTP and PCr responses to hypoxia by hypothermic and normothermic respiring, superfused, neonatal rat cerebrocortical slices: an NMR spectroscopy study at 14.1 Tesla.- Matrix metalloproteinases are not involved in early brain edema formation after cardiac arrest in rats.- Regional N-acetyl-aspartate level and immunohistochemical damage in the hippocampus after transient forebrain ischemia in gerbils.- Extracellular superoxide dismutase following cerebral ischemia in mice.- Peroxynitrite and caspase-3 expression after ischemia/reperfusion in mouse cardiac arrest model.- Expression oftumor necrosis factor ? (TNF?) following transient cerebral ischemia.- Evaluation of neuronal cell death after a new global ischemia model in infant mice.- Hippocampal heme oxigenase-1 in a murine cardiac arrest model.- Calcineurin and cyclophilin D are differential targets of neuroprotection by immunosuppressants CsA and FK506 in ischemic brain damage.- FK506 attenuates the post-ischemic perturbation of protein kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors.- Blood-brain barrier dysfunction and amyloid precursor protein accumulation in microvascular compartment following ischemia-reperfusion brain injury with 1-year survival.- Neuroprotective effect from ischemia and direct free radical scavenging activity of Choto-san (kampo medicine).- Experimental focal ischemia.- Temporal profile of experimental ischemic edema after threshold amount of insult to induce infarction-ultrastructure, gravimetry and Evans’ blue extravasation.- Prediction of tissue survival after stroke based on changes in the apparent diffusion of water (cytotoxic edema).- Recovery of apparent diffusion coefficient after embolic stroke does not signify complete salvage of post-ischemic neuronal tissue.- Temporal evolution of apparent diffusion coefficient and T2 value following transient focal cerebral ischemia in gerbils.- Prediction of malignant infarction: perifocal neurochemical monitoring following prolonged MCA occlusion in cats.- A comparison of long-term neurological symptoms after two different focal ischemic models in Mongolian gerbils.- Thrombin exacerbates brain edema in focal cerebral ischemia.- Infiltration of tissue plasminogen activator through cerebral vessels: evaluation using a rat thromboembolic stroke model.- Mice deficient in cytosolic phospholipase A2 are less susceptible to cerebral ischemia/reperfusion injury.- Regional distribution of potassium and phosphorus in ischemic brain tissue of rats with X-ray fluorescence analysis.- Changes of free cholesterol and neutrallipids after transient focal brain ischemia in rats.- Osteopontin infusion into normal adult rat brain fails to increase cell proliferation in dentate gyrus and subventricular zone.- Dissociative increase of oligodendrocyte progenitor cells between young and aged rats after transient cerebral ischemia.- Suppression of oxidative stress after transient focal ischemia in interleukin-1 knock out mice.- Mild hypothermia enhances the neuroprotective effects of a selective thrombin inhibitor following transient focal ischemia in rats.- The neuroprotective effect of a free radical scavenger and mild hypothermia following transient focal ischemia in rats.- Therapeutical efficacy of a novel non-peptide bradykinin B2 receptor antagonist on brain edema formation and ischemic tissue damage in focal cerebral ischemia.- Iodoamphetamine (IMP) uptake in the brain is increased after experimental cerebral venous hypertension in the rat.- Vasogenic edema and VEGF expression in a rat two-vein occlusion model.- Astroglial swelling in the neuronal depolarization ensemble.- An Na+/H+ exchanger inhibitor suppresses cellular swelling and neuronal death induced by glutamate in cultured cortical neurons.- Akt phosphorylation and cell survival after hypoxia-induced cytochrome c release in superfused respiring neonatal rat cerebrocortical slices.- The spinal GDNF level is increased after transient spinal cord ischemia in the rat.- Clinical ischemia.- Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis.- Cerebral blood flow index image as a simple indicator for the fate of acute ischemic lesion.- Transient elevation of serum Bilirubin (a heme oxygenase-1 metabolite) level in hemorrhagic stroke: bilirubin is a marker of oxidant stress.- Relation between brain oxygen metabolism and temperature gradient between brain and bladder.- Experimental trauma.- Neuropeptide release influences brain edema formation after diffuse traumatic brain injury.- Modulation of Aquaporin-4 water transport in a model of TBI.- Correlation of lesion volume and brain swelling from a focal brain trauma.- A role of glial fibrillary acidic protein in hippocampal degenerat ion after cerebral trauma or kainateinduced seizure.- Antioxidant properties of the vasoactive endocann abinoid, 2-arachidonoyl glycerol (2-AG).- Very early expression of vascular endo thelial growth factor in brain oedema tissue associated with brain contusion.- Changes of perivascular macrophages in the process of brain edema induced by cold injury.- Mitogen-activated protein kinases phosphorylation in posttraumat ic selective vulnerability in rats.- Treatment of cold injury-induced brain edema with a nonspecific matrix metalloproteinase inhibitor MM1270 in rats.- Prions prevent brain damage after experimental brain injury: a preliminary report.- The effect of Cyc1osporin A on brain edema formation following experimental cortic al contusion.- The glutamate AMPA receptor antagonist, YM872, attenuates regional cerebral edema and IgG immunoreactivity following experimental brain injury in rats.- Effects of edara vone on experimental brain injury in view of free radical reaction.- Antioxidant compounds EGB-761 and BN-52021 attenuate brain edema formation and hemeoxygenase expression following hyperthermic brain injury in the rat.- Clinical trauma.- Edema fluid accumulation within necrotic brain tissue as a cause of the mass effect of cerebral contusion in head trauma patients.- Ultra-early study of edema formation in cerebral contusion using diffusion MRI and ADC mapping.- Mixed dishomogeneous hemorrhagic brain contusions. Mapping of cerebral blood flow.- Neuronal damage in pericontusional edema zone.- Characteristics of parietal-parasagittal hemorrhage after mild or moderate traumatic brain injury.- L-8 is a key mediator of neuroinflammation in severe traumatic brain injuries.- The risk factors for the occurrence of acute brain swelling in acute subdural hematoma.- Volume-targeted therapy of increased intracranial pressure.- Induced acute arterial hypertension and regional cerebral flow in intracontusional low density area.- The importance of decompressive craniectomy for the management of severe head injuries.- Importance of hemodynamics management in patients with severe head injury and during hypothermia.- Changes in cerebro vascular response during brain hypothermia after traumatic brain injury.- Spinal cord trauma.- Neurotrophic factors attenuate microvascular permeability disturbances and axonal injury following trauma to the rat spinal cord.- Depletion of endogenous serotonin synthesis with p-CPA attenuates upregulation of constitutive isoform of heme oxygenase-2 expression, edema formation and cell injury following a focal trauma to the rat spinal cord.- High frequency electrical stimulation attenuates progressive necrosis and cavitation following spinal cord injury.- Low molecular weight compounds with affinity to melanocortin receptors exert neuroprotection in spinal cord injury.- Topical application of TNF-? antiserum attenuates spinal cord trauma induced edema formation, microvascular permeability disturbances and cell injury in the rat.- A new antioxidant compound H-290/51 attenuates spinal cord injury induced expression of constitutive and inducible isoforms of nitric oxide synthase and edema formation in the rat.- Src family kinase inhibition PPl improves motor function by reducing edema after spinal cord contusion in rats.- An L-type calcium channel blocker, nimodipine influences trauma induced spinal cord conduction and axonal injury in the rat.- Multiple hyperbaric oxygenation (HBO) expands the therapeutic window in acute spinal cord injury in rats.- Intracerebral and subarachnoid hemorrhage.- The international surgical trial in intracerebral haemorrhage (ISTICH).- Chronological changes of perihematomal edema of human intracerebral hematoma.- Thrombin preconditoning upregulates transferrin and transferrin receptor and reduces brain edema induced by lysed red blood cells.- Effect of hypothermia on brain edema formation following intracerebral hemorrhage in rats.- Effect of delayed argatroban treatment on intracerebral hemorrhage-induced edema in the rat.- Overexpression of interleukin-1 receptor antagonist reduces brain edema induced by intracerebral hemorrhage and thrombin.- The role of haematoma aspiration in the management of patients with thalamic haemorrhage: a pilot study with continuous compliance monitoring.- Acute decrease of cerebrocortical microflow and lack of carbon dioxide reactivity following subarachnoid haemorrhage in the rat.- Heat shock proteins expression in brain stem after subarachnoid hemorrhage in rats.- Apoptosis, blood-brain barrier, and subarachnoid hemorrhage.- Focal brain edema and natriuretic peptides in patients with subarachnoid hemorrhage.- Tumor.- Aquaporin 1 and Aquaporin 4 expression in human brain after subarachnoid hemorrhage and in peritumoral tissue.- Aquaporin-1 expression in human glial tumors suggests a potential novel therapeutic target for tumor-associated edema.- A thrombin inhibitor reduces brain edema, glioma mass and neurological deficits in a rat glioma model.- Tissue reconstruction process in the area of peri-tumoural oedema caused by glioblastoma - immunohistochemical and graphical analysis using brain obtained at autopsy.- Radiation necrosis and brain edema association with CyberKnife treatment.- Vacular endothelial growth factor expression in pituitary adenomas.- Hydrocephalus.- Aquaporin-1 delection reduces osmotic water permeability and cerebrospinal fluid production.- Hysteresis of the cerebrospinal pressure-volume curve in hydrocephalus.- Is decreased ventricular volume a correlate of positive clinical outcome following shunt placement in cases of normal pressure hydrocephalus?.- The ICP-dependency of resistance to cerebrospinal fluid outflow: a new mathematical method for CSF-parameter calculation in a model with H-Tx rats.- Metabolic derangements in interstitial brain edema with pre served blood flow: selective vulnerability of the hippocampal CA3 region in rat hydrocephalus.- MRI analysis of hydrocephalus associated with acoustic neurinoma.- Blood brain barrier, miscellaneous.- Non-invasive opening of BBB by focused ultrasound.- Quantitative analysis of hyperosmotic and hypothermic blood-brain barrier opening.- Chronic adrenomedullin treatment improves blood-brain barrier function but has no effects on expression of tight junction proteins.- Blood brain barrier.- Characteristic phosphorylation of the extracellular signal-regulated kinase pathway after kainate-induced seizures in the rat hippocampus.- Highly polysialylated neural cell adhesion molecule (PSA-NCAM) positive cells are increased and change localization in rat hippocampus by exposure to repeated kindled seizures.- Continuous assessment of cerebral autoregulation : clinical and lab oratory experience.- Spontaneous intracrani al hypotension (SIH): the early appearance of urinary bladder activity in RI cisternography is a pathognomonic sign of SIH?.- Roundtable discussion (Brain Edema 2002).- Hakone best presentation award.- Author Index.- Index of Keywords.