Mark A. Geyer,
Gerhard Gross
Springer Berlin Heidelberg
2012e druk, 2014
9783642438097
Novel Antischizophrenia Treatments
Specificaties
Paperback, 458 blz.
|
Engels
Springer Berlin Heidelberg |
2012e druk, 2014
ISBN13: 9783642438097
Rubricering
Onderdeel van serie
Handbook of Experimental Pharmacology
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Specificaties
ISBN13:9783642438097
Taal:Engels
Bindwijze:paperback
Aantal pagina's:458
Uitgever:Springer Berlin Heidelberg
Druk:2012
Inhoudsopgave
<p>Preface.- Clinical instruments to evaluate and guide treatment in schizophrenia.- Cognitive deficits in schizophrenia- Muscarinic mechanisms in psychotic disorders.- Nicotinic mechanisms in psychotic disorders.- GABAergic circuits in schizophrenia: targets for new treatments in schizophrenia.- Inhibitors of glycine transport as potential new treatments in schizophrenia.- The role of glutamate in schizophrenia.- Metabotropic glutamate receptors as targets for new treatments in schizophrenia.- 5-HT2C agonism as a principle for new treatments in schizophrenia.- The role of dopamine D3 receptors for antipsychotic activity and cognitive functions.- Phosphodiesterase inhibitors as potential new treatments in schizophrenia.- Disease modifying approaches to schizophrenia.- A novel therapeutic strategy: medication-enhancement of cognitive therapies in schizophrenia.- Transgenic animals reflecting aspects of schizophrenia.- Behavioral animal models of pro-cognitive treatments for schizophrenia. </p><p>