Joaquín Arino,
Denis Alexander
Springer Berlin Heidelberg
0e druk, 2011
9783642058172
Protein Phosphatases
Specificaties
Paperback, 378 blz.
|
Engels
Springer Berlin Heidelberg |
0e druk, 2011
ISBN13: 9783642058172
Rubricering
Onderdeel van serie
Topics in Current Genetics
Levertijd ongeveer 8 werkdagen
Samenvatting
This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes.
The book covers dephosphorylation processes involving serine/threonine, as well as tyrosine and histidine residues, and aims to be a useful resource for both the advanced reader as well as the newcomer to the field. It is also valuable for those working in the pharmaceutical and Biotech industries.
Specificaties
ISBN13:9783642058172
Taal:Engels
Bindwijze:paperback
Aantal pagina's:378
Uitgever:Springer Berlin Heidelberg
Druk:0
Inhoudsopgave
Overview of Protein Serine/Threonine Phosphatases.- Protein Phosphatase 1.- Protein Phosphatase 2A: A Multifunctional Regulator of Cell Signaling.- Calcineurin: Roles of the Ca2+/Calmodulin-dependent Protein Phosphatase in Diverse Eukaryotes.- Roles of Mammalian Protein Phosphatase 2C Family Members in the Regulation of Cellular Functions.- PP5: the TPR Phosphatase.- Protein Histidine Phosphatases in Signal Transduction and Metabolism.- Anchoring of Protein Kinase and Phosphatase Signaling Units.- Functional Proteomics in Phosphatase Research.- Structure and Function of the T-cell Protein Tyrosine Phosphatase.- Protein Tyrosine Phosphatase-based Therapeutics: Lessons From PTP1B.- The CD45 Phosphotyrosine Phosphatase.- Receptor Protein Tyrosine Phosphatases.- The Shp-2 Tyrosine Phosphatase.- SHP-1 Twelve Years on: Structure, Ligands, Substrates and Biological Roles.- The Dual-specific Protein Tyrosine Phosphatase Family.- Tyrosine Phosphatases in Cancer: Targets for Therapeutic Intervention.