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Information Geometry and Population Genetics

The Mathematical Structure of the Wright-Fisher Model

Specificaties
Paperback, blz. | Engels
Springer International Publishing | e druk, 2018
ISBN13: 9783319848051
Rubricering
Springer International Publishing e druk, 2018 9783319848051
Onderdeel van serie Understanding Complex Systems
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.

Specificaties

ISBN13:9783319848051
Taal:Engels
Bindwijze:paperback
Uitgever:Springer International Publishing

Inhoudsopgave

<p>1. Introduction.- 2. The Wright–Fisher model.- 3. Geometric structures and information geometry.- 4. Continuous approximations.- 5. Recombination.- 6. Moment generating and free energy functionals.- 7. Large deviation theory.- &nbsp;8. The forward equation.- 9. The backward equation.- 10.Applications.- Appendix.- A. Hypergeometric functions and their generalizations.- Bibliography.</p>

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        Information Geometry and Population Genetics