<div>I. Physiology and Development of Enteric Neuromuscular System and Gastrointestinal Motility </div><div><br></div><div>1. Introduction</div><div>Christophe Faure, Nikhil Thapar, and Carlo Di Lorenzo</div><div><br></div><div>2. Development of the Enteric Neuromuscular System</div><div>Tiffany A. Heanue and Alan J. Burns</div><div><br></div>3. Development of Gut Motility<div>Elizabeth A. Beckett, Heather M. Young, Joel C. Bornstein, and Sudarshan R. Jadcherla </div><div><br></div><div>4. Visceral Sensitivity</div><div>Christopher Faure and Fransziska Righini-Grunder</div><div><br></div><div>5.The Microbiome in Neurogastroenterology</div><div>Geoffrey A. Preidis, Bruno P. Chumpitazi, and Robert J. Shulman</div><div><br>6. Integration of Biomedical and Psychosocial Issues in Pediatric Functional Gastrointestinal and Motility Disorders </div><div>Miranda A. L. van Tilburg</div><div><br></div><div>II. Motility and Sensory Testing</div><div><br></div><div>7. Esophageal Manometry</div><div>Rossella Turco and Annamaria Staiano</div><div><br></div>8. Antroduodenal Manometry<div>Efstratios Saliakellis, Anna Rybak, Nikhil Thapar, and Osvaldo Borrelli </div><div><br></div><div>9. Colonic Manometry</div><div>Desale Yacob and Carlo Di Lorenzo </div><div><br></div><div>10. Anorectal Manometry</div><div>Claire Zar-Kessler and Jaime Belkind-Gerson</div><div><br></div>11. Assessment of Feeding and Swallowing Disorders<div>Nathalie Rommel </div><div><br></div><div>12- Esophageal pH and Impedance Monitoring</div><div>Eric Chiou and Rachel L. Rosen </div><div><br></div><div>13. Barostat and Other Sensitivity Tests</div><div>Christophe Faure</div><div>14. Radionuclide Gastrointestinal Transit Tests</div><br><div>Lorenzo Biassoni, Marina Easty, and Osvaldo Borrelli</div><div><br></div><div>15. Electrogastrography, Breath Tests, Ultrasonography, Transit Tests, and SmartPill</div><div>Ricardo A. Arbizu and Leonel Rodriguez</div><div><br><div>16. Autonomic Nervous System Testing</div><div>Gisela Chelimsky and Thomas C. Chelimsky </div><div><br></div>III. Disorders of Digestive Motility<div><br></div><div>17. Pathology of Enteric Neuromuscular Disorders</div><div>Raj P. Kapur</div><div><br></div><div>18. Genetics of Motility Disorder: Gastroesophageal Reflux, Triple A Syndrome, Hirschsprung Disease, and Chronic Intestinal Pseudo-Obstruction</div><div>Jonathan M. Gisser and Cheryl E. Gariepy </div><div><br></div>19. Allergy and Neurogastroenterology<div>Osvaldo Borrelli, Roberto Conti Nibali, and Nikhil Thapar<br></div><div><br></div><div>20. Swallowing and Oropharyngeal Disorders</div><div>Daniel R. Duncan and Rachel L. Rosen</div><div><br></div><div>21. Esophageal Achalasia</div><div>Ann Aspirot</div><div><br></div>22. Other Esophageal Motility Disorders<div>Hayat Mousa</div><div><br></div><div>23. Gastric Motor Disorders</div><div>John M. Rosen and Miguel Saps</div><div><br></div><div>24. Pediatric Chronic Intestinal Pseudo-Obstruction</div><div>Efstratios Saliakellis, Christophe Faure, Nikhil Thapar</div><div><br></div>25. Hirschsprung Disease<div>Robert O. Heuckeroth</div><div><br></div><div>26. Motility Problems in Developmental Disorders: Cerebral Palsy, Down Syndrome, Williams Syndrome, Autism, Turner’s Syndrome, Noonan’s Syndrome, Rett Syndrome and Prader Willi</div><div>Massimo Martinelli and Annamaria Staiano</div><div><br></div><div>27. Familial Dysautonomia and Mitochondrial Disorders</div>Massimo Martinelli and Annamaria Staiano<div><br></div><div>IV. Motility Disorders After Surgery and Developmental Anomalies of the Enteric Neuromuscular System Secondary to Anatomical Malformations</div><div><br></div><div>28. Esophageal Atresia</div><div>Fransziska Righini-Grunder and Christophe Faure</div><div><br></div><div>29. Anorectal Malformations</div><div>Ann Aspirot</div><br><div>30. Motility After Small Bowel and Colonic Surgery</div><div>Roberto Gomez and John E. Fortunato </div><div><br></div><div>31. Gastric Function After Fundoplication</div><div>Samuel Nurko </div><div><br></div><div>32. Rome Criteria for Functional Gastrointestinal Disorders</div>Samuel Nurko and Carlo Di Lorenzo<div><br></div><div>33. Infant Regurgitation and Pediatric Gastroesophageal Reflux Disease </div><div>Yvan Vandenplas</div><div><br></div><div>34. Infant Colic</div><div>Valerie Sung and Ian St James-Roberts </div><div><br></div><div>35. Functional Diarrhea in Toddlers (Chronic Nonspecific Diarrhea)</div>Ernesto Guiraldes and José Luis Roessler <div><br></div><div>36. Functional Dyspepsia</div><div>John M. Rosen and Miguel Saps</div><div><br></div><div>37. Irritable Bowel Syndrome</div><div>Jasmeet S. Mokha and Jeffrey S. Hyams </div><div><br></div><div>38. Functional Abdominal Pain</div>Manu R. Sood and Katja Kovacic<div><br></div><div>39. Cyclic Vomiting Syndrome: Comorbidities and Treatment</div><div>B U. K. Li and Katja Kovacic </div><div><br></div><div>40. Aerophagia</div><div>Carlo Di Lorenzo</div><div><br></div><div>41. Rumination Syndrome</div><div>Anthony Alioto and Carlo Di Lorenzo </div><div><br></div><div>42. Functional Constipation in Children</div><div>Ilan J. N. Koppen and Marc A. Benninga</div><div><br></div><div>43. Fecal Incontinence in Children</div><div>Ilan J. N. Koppen and Marc A. Benninga</div><div><br></div><div>VI. Treatments</div><div><br></div>44. Drugs Acting on the Gut: Prokinetics, Antispasmodics, Laxatives<div>Aileen F. Har and Joseph M. B. Croffie</div><div><br></div><div>45. Drugs That Work in the Brain</div><div>Paul E. Hyman and Rami Arrouk</div><div><br></div><div>46. Electrical Stimulation of the GI Tract</div><div>Steven Teich</div><div><br></div>47. Cognitive Behavioral Therapy for Functional Gastrointestinal Disorders<div>Miranda A. L. van Tilburg </div><div><br>48. Complementary and Alternative Treatments for Motility and Sensory Disorders</div><div>Arine M. Vlieger and Marc A. Benninga </div><div><br></div><div>49. Cellular Based Therapies for Pediatric GI Motility Disorders</div>Ryo Hotta, Dipa Natarajan, Alan J. Burns, and Nikhil Thapar<div><br></div><div>50. Chronic Intestinal Pseudo-Obstruction Syndrome: Surgical Approach and Intestinal Transplantation</div><div>Olivier Goulet and Sabine Irtan </div>