Inflammation in Parkinson's Disease

Scientific and Clinical Aspects

Specificaties
Gebonden, 222 blz. | Engels
Springer International Publishing | 2014e druk, 2014
ISBN13: 9783319080451
Rubricering
Springer International Publishing 2014e druk, 2014 9783319080451
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Samenvatting

Parkinson’s Disease (PD) is a progressive neurodegenerative disease with a prevalence of 0.1% of the global population, and 5-10% patients are under 40 years of age. Several text books have been published on various aspects of PD to date, including research and clinical aspects. However these do not emphasize the inflammatory pathways and pathways of neurodegeneration in PD. Inflammation in Parkinson’s Disease brings advances in research together with current literature and evidence. This concise volume covers the fundamentals of neuroimmunology and inflammatory models, the interactions between pathways of neurodegeneration and follows the concept of research work undertaken from basic science to clinical trials. Researchers, clinicians, and students interested in Parkinson's Disease are provided with a comprehensive view of translational research methods and an insight needed for developing future therapies aimed at disease modulation.

Specificaties

ISBN13:9783319080451
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:222
Uitgever:Springer International Publishing
Druk:2014

Inhoudsopgave

<p>1. Parkinson’s Disease: An Overview of Etiology, Clinical Manifestations, and Treatment . - 2. Neuropathology of Parkinson’s Disease. - 3. Role of the Innate and Adaptive Immune System in the Pathogenesis of PD. - 4. “Good” and “Bad” Microglia in Parkinson’s Disease: An Understanding of Homeostatic Mechanisms in Immunomodulation . - 5. The Role of Astrocytes in Parkinson’s Disease. -  6. Proinflammatory Chemical Signaling: Cytokines. - 7. Cell Culture Models of Inflammation in Parkinson’s Disease. - 8. Clinical Aspects of Inflammation in Parkinson’s Disease . - 9. PET Imaging in Neuroinflammation.</p><p><p><p><p><p><p><p><p><p>

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        Inflammation in Parkinson's Disease