Anton G. Kutikhin,
Arseniy E. Yuzhalin
Springer Basel
2013e druk, 2013
9783034806879
Genomics of Pattern Recognition Receptors
Applications in Oncology and Cardiovascular Diseases
Specificaties
Gebonden, 185 blz.
|
Engels
Springer Basel |
2013e druk, 2013
ISBN13: 9783034806879
Rubricering
Levertijd ongeveer 8 werkdagen
Samenvatting
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
Specificaties
ISBN13:9783034806879
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:185
Uitgever:Springer Basel
Druk:2013
Inhoudsopgave
<p>The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation.- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword.- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer.- Structural Genomic Variation in Other Toll-like Receptors and Cancer.- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer.- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer.- Structural Genomic Variation in NOD-Like Receptors and Cancer.- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases.- Hot Spots In the Field: Where Should We Go.</p>