<p>Introduction.- Assays for thiols and modifications.- Pitfalls of ROS measurements by fluorescent probes and mitochondrial superoxide determination using MitoSOX.- Methods and Reagents.- Clinical Probes for ROS and Oxidative Stress.- Measurement of oxidative stress markers in vitro using commercially available kits.- Oxidative Lipidomics - Analysis of Oxidized Lipids and Lipid Peroxidation in Biological Systems with Relevance to Health & Disease.- Clinically Related Models and Approaches.- Oxidant-Induced Models of Vascular Leak.- Ozone-Specific’ Oxysterols and Neuronal Cell Signaling.- Measurement Oxidative Stress Status in Human Populations: A Critical Need for a Metabolomic Approach.- Instrumental Methods.- Sense and Sensibility of Oxygen in Pathophysiology using EPR Oximetry.- Resonators for Clinical EPR.- Biomedical Overhauser Magnetic Resonance Imaging (OMRI). Noninvasive Imaging of Redox Processes.- Index.</p>