<p>1. Chemical Probe Development Versus Drug Development</p><p> Michael R. Jackson</p><p> </p><p>2. Phosphatase High-Throughput Screening Assay Design and Selection</p><p> Eduard A. Sergienko</p><p> </p><p>3. Multisystemic Functions of Alkaline Phosphatases</p><p> René Buchet, José Luis Millán, and David Magne</p><p> </p><p>4. Robotic Implementation of Assays: Tissue-Nonspecific Alkaline Phosphatase (TNAP) Case Study</p><p> Thomas D.Y. Chung</p><p> </p><p>5. Inhibitors of Tissue-Nonspecific Alkaline Phosphatase (TNAP): From Hits to Leads</p><p> Peter Teriete, Anthony B. Pinkerton, and Nicholas D.P. Cosford</p><p> </p><p>6. A Method for Direct Assessment of Tissue-Nonspecific Alkaline Phosphatase (TNAP) Inhibitors in Blood Samples</p><p> Eduard Sergienko, Qing Sun, and Chen-Ting Ma</p><p> </p><p>7. Isolation and Characteristics of Matrix Vesicles</p><p> René Buchet, Slawomir Pikula, David Magne, and Saïda Mebarek</p><p> </p><p>8. The Use of Tissue-Nonspecific Alkaline Phosphatase (TNAP) and PHOSPHO1 Inhibitors to Affect Mineralization by Cultured Cells</p><p> Tina Kiffer-Moreira and Sonoko Narisawa</p><p> </p><p>9. Modulators of Intestinal Alkaline Phosphatase</p><p> Ekaterina V. Bobkova, Tina Kiffer-Moreira, and Eduard A. Sergienko</p><p> </p><p>10. New Activity Assays for ENPP1 with Physiological Substrates ATP and ADP</p><p> Chen-Ting Ma and Eduard Sergienko</p><p> </p><p>11. Structure of Acid Phosphatases</p><p> César L. Araujo and Pirkko T. Vihko</p><p> </p><p>12. Purification of Prostatic Acid Phosphatase (PAP) for Structural and Functional Studies</p><p> Annakaisa M. Herrala, Ileana B. Quintero, and Pirkko T. Vihko</p><p> </p><p>13. Protein Tyrosine Phosphatases: Structure, Function, and Implication in Human Disease</p><p> Lutz Tautz, David A. Critton, and Stefan Grotegut</p><p> </p><p>14. High-Throughput Screening for Protein Tyrosine Phosphatase Activity Modulators</p><p> Lutz Tautz and Eduard A. Sergienko</p><p> </p><p>15. Evaluating Effects of Tyrosine Phosphatase Inhibitors on T Cell Receptor Signaling</p><p> Souad Rahmouni, Laurence Delacroix, Wallace H. Liu, and Lutz Tautz</p><p> </p><p>16. Interactor-Guided Dephosphorylation by Protein Phosphatase-1</p><p> Shannah Boens, Kathelijne Szekér, Aleyde Van Eynde, and Mathieu Bollen</p><p> </p><p>17. Structure, Regulation, and Pharmacological Modulation of PP2A Phosphatases</p><p> Caroline Lambrecht, Dorien Haesen, Ward Sents, Elitsa Ivanova, and Veerle Janssens</p>
