Mass Spectrometry Data Analysis in Proteomics

Specificaties
Gebonden, 405 blz. | Engels
Humana Press | 2e druk, 2013
ISBN13: 9781627033916
Rubricering
Humana Press 2e druk, 2013 9781627033916
Onderdeel van serie Methods in Molecular Biology
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Since the publishing of the first edition, the methodologies and instrumentation involved in the field of mass spectrometry-based proteomics has improved considerably.  Fully revised and expanded, Mass Spectrometry Data Analysis in Proteomics, Second Edition presents expert chapters on specific MS-based methods or data analysis strategies in proteomics. The volume covers data analysis topics relevant for quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards, among other topics.  Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Updated and authoritative, Mass Spectrometry Data Analysis in Proteomics, Second Edition serves as a detailed guide for all researchers seeking to further our knowledge in the field of proteomics.

Specificaties

ISBN13:9781627033916
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:405
Uitgever:Humana Press
Druk:2

Inhoudsopgave

<p>1. Introduction to Mass Spectrometry-Based Proteomics</p><p>            Rune Matthiesen and Jakob Bunkenborg</p><p> </p><p>2. LC-MS Spectra Processing</p><p>            Rune Matthiesen</p><p> </p><p>3. Isotopic Distributions</p><p>            Alan L. Rockwood and Magnus Palmblad</p><p> </p><p>4. Retention Time Prediction and Protein Identification</p><p>            Alex A. Henneman and Magnus Palmblad</p><p> </p><p>5. Algorithms for Database Dependent Search of MSMS Data</p><p>            Rune Matthiesen</p><p> </p><p>6. Interpretation of Tandem Mass Spectra of Post-Translationally Modified Peptides</p><p>            Jakob Bunkenborg and Rune Matthiesen</p><p> </p><p>7. Improving Peptide Identification Using Empirical Scoring Systems</p><p>            Robert J. Chalkley</p><p> </p><p>8. Methods and Algorithms for Quantitative Proteomics by Mass Spectrometry</p><p>            Rune Matthiesen and Ana Sofia Carvalho</p><p> </p><p>9. Computational Approaches to Selected Reaction Monitoring (SRM) Assay Design</p><p>            Conrad Bessant and Jun Fan</p><p> </p><p>10. Feature Selection and Machine Learning with Mass Spectrometry Data</p><p>            Susmita Datta</p><p> </p><p>11. Considerations in the Analysis of Hydrogen Exchange Mass Spectrometry Data</p><p>            Thomas E. Wales, Michael J. Eggertson, and John R. Engen</p><p> </p><p>12. Permethylated N-Glycan Analysis with Mass Spectrometry</p><p>            Zhenxin Lin and David M. Lubman</p><p> </p><p>13. Mass Spectrometry Methods for Studying Glycosylation in Cancer</p><p>            Hugo Osório and Celso A. Reis</p><p> </p><p>14. Proteomics Data Exchange and Storage: The Need for Common Standards and Public Repositories</p><p>            Rafael C. Jiménez and Juan Antonio Vizcaíno</p><p> </p><p>15. Tools for Protein Post Translational Modifications Analysis: FAK, A Case Study</p><p>            Catarina Fonseca, Paula Voabil, Ana Sofia Carvalho, and Rune Matthiesen</p><p> </p><p>16. Proteomic Strategies to Characterize Signaling Pathways</p><p>            H.C. Harsha, Sneha M. Pinto, and Akhilesh Pandey</p><p> </p><p>17. Simple Proteomics Data Analysis in the Object-Oriented PowerShell</p><p>            Yassene Mohammed and Magnus Palmblad</p>

Rubrieken

    Personen

      Trefwoorden

        Mass Spectrometry Data Analysis in Proteomics