Peptide-Based Drug Design

1 Peptide-based Drug Design: Here and Now Laszlo Otvos, Jr. 2 Strategies for the Discovery, Isolation, and Characterization of Natural Bioactive Peptides from the Immune System of Invertebrates Philippe Bulet 3 Sequence Analysis of Antimicrobial Peptides by Tandem Mass Spectrometry Christin Stegemann and Ralf Hoffmann 4 The Spot Technique: Synthesis and Screening of Peptide Macroarrays on Cellulose Membranes Dirk F.H. Winkler and William D. Campbell 5 Analysis of Abeta interactions using ProteinChip Technology Eleni Giannakis, Lin-Wai Hung, Keyla Perez Camacaro, David P. Smith, Kevin J. Barnham, and John D. Wade 6 NMR in Peptide Drug Development Jan-Christoph Westermann and David J Craik 7 Molecular Dynamics Simulations of Peptides Jeffrey Copps, Richard F. Murphy, and Sándor Lovas 8 Short Linear Cationic Antimicrobial Peptides – Screening, Optimizing and Prediction Kai Hilpert, Christopher D Fjell, and Artem Cherkasov 9 Investigation of the Mode of Action of Proline-rich Antimicrobial Peptides: Genetic and Cytometric Approaches. Marco Scocchi, Maura Mattiuzzo, Monica Benincasa, Nikolinka Antcheva, Alessandro Tossi, and Renato Gennaro 10 Serum Stability of Peptides Håvard Jenssen and Stein Ivar Aspmo 11 Preparation of Glycosylated Amino Acids Suitable for Fmoc Solid-Phase Assembly Mare Cudic and Gayle D. Burstein 12 Synthesis of O-Phosphopeptides on Solid Phase David Singer and Ralf Hoffmann 13 Peptidomimetics: Fmoc Solid-Phase Pseudopeptide Synthesis Predrag Cudic and Maciej Stawikowski 14 Synthesis of Toll-like Receptor-2 Targeting Lipopeptides as Self-Adjuvanting Vaccines Brendon Y. Chua, Weiguang Zeng & David C.Jackson 15 Synthesis of a Multivalent, Multiepitope Vaccine Construct Laszlo Otvos, Jr. 16 Cysteine-Containing Fusion Tag for Site-Specific Conjugation of Therapeutic and Imaging Agents to Targeting Proteins Marina V. Backer, Zoia Levashova, Richard Levenson, Francis G. Blankenberg, and Joseph M. Backer