Uttam Garg,
Catherine A. Hammett-Stabler
Humana Press
2010e druk, 2009
9781607614586
Clinical Applications of Mass Spectrometry
Methods and Protocols
Specificaties
Gebonden, 540 blz.
|
Engels
Humana Press |
2010e druk, 2009
ISBN13: 9781607614586
Rubricering
Onderdeel van serie
Methods in Molecular Biology
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic compounds spanning the disciplines of toxicology, therapeutic drug monitoring, endocrinology, and pediatric metabolism. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to the analytes, lists of the necessary materials and reagents, readily reproducible analytical protocols, and detailed notes on troubleshooting and avoiding known pitfalls.
Comprehensive and dependable, Clinical Applications of Mass Spectrometry: Methods and Protocols offers its readers a wide array of valuable methods for experienced mass spectrometric labs that are looking to introduce new analyses as well as for those laboratories currently considering the addition of this resourceful and vital technology.
Specificaties
ISBN13:9781607614586
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:540
Uitgever:Humana Press
Druk:2010
Inhoudsopgave
<P>1. The Evolution of Mass Spectrometry in the Clinical Laboratory</P>
<P>Catherine A. Hammett-Stabler and Uttam Garg</P>
<P></P>
<P>2. Measurement of Plasma/Serum Acylcarnitines Using Tandem Mass Spectrometry</P>
<P>Nathalie Lepage and Susan Aucoin</P>
<P></P>
<P>3. Comprehensive Determination of Amino Acids for Diagnosis of Inborn Errors of Metabolism </P>
<P>Dennis J. Dietzen and Annette L. Weindel</P>
<P></P>
<P>4. Identification and Quantitation of Amphetamine, Methamphetamine, MDMA, Pseudoephedrine, and Ephedrine in Blood, Plasma, and Serum Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>5. Quantification of Antidepressants Using Gas Chromatography-Mass Spectrometry</P>
<P>Ruth E. Winecker</P>
<P></P>
<P>6. Quantitation of Argatroban in Plasma using Liquid Chromatography Electrospray Tandem Mass Spectrometry (UPLC-ESI-MS/MS)</P>
<P>Ross J. Molinaro</P>
<P></P>
<P>7. Quantitation of Amobarbital, Butalbital, Pentobarbital, Phenobarbital, and Secobarbital in Urine, Serum, and Plasma Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Leonard L. Johnson and Uttam Garg</P>
<P></P>
<P>8. Quantitation of Benzodiazepines in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>9. LC-MS/MS Analysis of 13 Benzodiazepines and Metabolites in Urine, Serum, Plasma, and Meconium</P>
<P>Stephanie J. Marin and Gwendolyn A. McMillin</P>
<P></P>
<P>10. Simultaneous Determination and Quantification of 12 Benzodiazepines in Serum or Whole Blood Using UPLC/MS/MS</P>
<P>Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>11. Determination of Benzoic Acid in Serum or Plasma by Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Jeff M. Knoblauch, David K. Scott, Laurie D. Smith, and Uttam Garg</P>
<P></P>
<P>12. Quantification of Busulfan in Plasma Uing Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS)</P>
<P>Marion L. Snyder and James C. Ritchie</P>
<P></P>
<P>13. Quantitation of Total 11-Nor-9-Carboxy-Delta 9-Tetrahydrocannabinol in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>C. Clinton Frazee III, Michael Kiscoan, and Uttam Garg</P>
<P></P>
<P>14. Quantitation of Cocaine, Benzoylecgonine, Ecgonine Methyl Ester, and Cocaethylene in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Steven W. Fleming, Amitava Dasgupta, and Uttam Garg</P>
<P></P>
<P>15. Identification and Quantitation of Cocaine, Benzoylecgonine, and Cocaethylene in Blood, Serum, and Plasma Using Ultra-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry (UPLC-MS/MS)</P>
<P>Scott Kriger, Josh Gunn, and Andrea R. Terrell</P>
<P></P>
<P>16. Detection and Quantification of Cocaine and Benzoylecgonine in Meconium Using Solid Phase Extraction and UPLC/MS/MS</P>
<P>Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>17. Diagnosis of Creatine Metabolism Disorders by Determining Creatine and Guanidinoacetate in Plasma and Urine </P>
<P>Qin Sun and William E. O'Brien</P>
<P></P>
<P>18. Broad Spectrum Drug Screening Using Electron-Ionization Gas Chromatography-Mass Spectrometry (EI-GCMS)</P>
<P>Judy Stone</P>
<P></P>
<P>19. Broad Spectrum Drug Screening Using Liquid Chromatography-Hybrid Triple Quadrupole Linear Ion Trap Mass Spectrometry</P>
<P>Judy Stone</P>
<P></P>
<P>20. High Sensitivity Measurement of Estrone and Estradiol in Serum and Plasma Using LC-MS/MS </P>
<P>Mark M. Kushnir, Alan L. Rockwood, Bingfang Yue, and A. Wayne Meikle</P>
<P></P>
<P>21. 3-Hydroxy-Fatty Acid Analysis by Gas Chromatography-Mass Spectrometry </P>
<P>Patricia M. Jones and Michael J. Bennett</P>
<P></P>
<P>22. Quantitation of Fentanyl in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>23. Determination of Total Homocysteine in Plasma Using Liquid Chromatography Coupled to Tandem Mass Spectrometry (LC/MS/MS)</P>
<P>Bruno Casetta</P>
<P></P>
<P>24. Quantitation of Homovanillic Acid (HVA) and Vanillylmandelic Acid (VMA) in Urine Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Ryan Allenbrand and Uttam Garg</P>
<P></P>
<P>25. Quantitation of 17-OH-Progesterone (OHPG) for Diagnosis of Congenital Adrenal Hyperplasia (CAH)</P>
<P>Ravinder J. Singh</P>
<P></P>
<P>26. Determination of Hydroxyurea in Serum or Plasma Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>David K. Scott, Kathleen Neville, and Uttam Garg</P>
<P></P>
<P>27. Quantitation of Ibuprofen in Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Gerry Huber and Uttam Garg</P>
<P></P>
<P>28. Quantitation of Indomethacin in Serum and Plasma Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Sarah Thomas, Amanda Sutton, and Uttam Garg</P>
<P></P>
<P>29. Quantitation of Iothalamate in Urine and Plasma Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS)</P>
<P>Ross J. Molinaro and James C. Ritchie</P>
<P></P>
<P>30. Identification and Quantitation of Ketamine in Biological Matrices Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Timothy P. Rohrig, Megan Gamble,<SUP> </SUP>and Kim Cox</P>
<P></P>
<P>31. Measurement of Filter Paper Bloodspot Lead by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) </P>
<P>Denise M. Timko and Douglas F. Stickle</P>
<P></P>
<P>32. Multiplex Lysosomal Enzyme Activity Assay on Dried Blood Spots Using Tandem Mass Spectrometry</P>
<P>X. Kate Zhang, Carole S. Elbin, Frantisek Turecek, Ronald Scott, Wei-Lien Chuang, Joan M. Keutzer, and Michael Gelb</P>
<P></P>
<P>33. Gas Chromatography-Mass Spectrometry Method for the Determination of Methadone and 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP)</P>
<P>Christine L.H. Snozek, Matthew W. Bjergum, and Loralie J. Langman</P>
<P></P>
<P>34. Liquid Chromatography-Tandem Mass Spectrometry (LC-MSMS) Method for Monitoring Methotrexate in the Setting of Carboxypeptidase-G2 Therapy</P>
<P>Vikram S. Kumar, Terence Law, and Mark Kellogg</P>
<P></P>
<P>35. Quantitation of Methylmalonic Acid in Serum or Plasma Using Isotope Dilution-Selected Ion Gas Chromatography-Mass Spectrometry</P>
<P>Jie Chen and Michael J. Bennett</P>
<P></P>
<P>36. Quantitation of Methylmalonic Acid in Plasma Using Liquid Chromatography–Tandem Mass Spectrometry</P>
<P>Claudine Fasching and Jasbir Singh</P>
<P></P>
<P>37. Monitoring of Mycophenolate Acid in Serum or Plasma Using LC Tandem Mass Spectrometry</P>
<P>Catherine A. Hammett-Stabler, Diane Ciuffetti Geis, James Ritchie, and Christine Papadea</P>
<P></P>
<P>38. Quantitation of Nicotine, Its Metabolites, and Other Related Alkaloids in Urine, Serum, and Plasma Using LC-MS/MS</P>
<P>Bingfang Yue, Mark M. Kushnir, Francis M. Urry, and Alan L. Rockwood</P>
<P></P>
<P>39. Quantitation of Opioids in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>40. Quantitation of Morphine, Codeine, Hydrocodone, Hydromorphone, Oxycodone, Oxymorphone, and 6-Monoacetylmorphine (6-MAM) in Urine, Blood, Serum, or Plasma Using Liquid Chromatography with Tandem Mass Spectrometry Detection</P>
<P>Tim Dahn, Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>41. Urine Organic Acid Analysis for Inherited Metabolic Disease Using Gas Chromatography-Mass Spectrometry</P>
<P>Patricia M. Jones and Michael J. Bennett</P>
<P></P>
<P>42. Identification of Urine Organic Acids for the Detection of Inborn Errors of Metabolism Using Urease and Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Stanley F. Lo,<SUP> </SUP>Velta Young, and William J. Rhead</P>
<P></P>
<P>43. Quantitation of Orotic Acid in Urine Using Isotope Dilution-Selected Ion Gas Chromatography-Mass Spectrometry</P>
<P>Jie Chen and Michael J. Bennett</P>
<P></P>
<P>44. Quantitation of Oxycodone in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>45. Quantitation of Phencyclidine (PCP) in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Angela M. Ferguson and Uttam Garg</P>
<P></P>
<P>46. Quantitation of Sirolimus Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS)</P>
<P>Magdalena Korecka and Leslie M. Shaw</P>
<P></P>
<P>47. Quantitation of Tacrolimus in Whole Blood Using High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC/MS/MS)</P>
<P>Keri J. Donaldson and Leslie M. Shaw</P>
<P></P>
<P>48. Analysis of Testosterone in Serum Using Mass Spectrometry</P>
<P>Robert L. Fitzgerald, Terrance L. Griffin, and David A. Herold</P>
<P></P>
<P>49. Determination of Tetrahydrozoline in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Judy Peat and Uttam Garg</P>
<P></P>
<P>50. Quantitation of 25-OH-Vitamin D (25OHD) Using Liquid Tandem Mass Spectrometry (LC-MS/MS)</P>
<P>Ravinder J. Singh</P>
<P></P>
<P>51. Identification and Quantitation of Zolpidem in Biological Matrices Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Timothy P. Rohrig, Lydia A. Harryman, and Melissa C. Norton</P>
<P></P>
<P>52. Identification and Quantitation of Zopiclone in Biological Matrices Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Timothy P. Rohrig, Melissa C. Norton, and Lydia A. Harryman</P>
<P>Catherine A. Hammett-Stabler and Uttam Garg</P>
<P></P>
<P>2. Measurement of Plasma/Serum Acylcarnitines Using Tandem Mass Spectrometry</P>
<P>Nathalie Lepage and Susan Aucoin</P>
<P></P>
<P>3. Comprehensive Determination of Amino Acids for Diagnosis of Inborn Errors of Metabolism </P>
<P>Dennis J. Dietzen and Annette L. Weindel</P>
<P></P>
<P>4. Identification and Quantitation of Amphetamine, Methamphetamine, MDMA, Pseudoephedrine, and Ephedrine in Blood, Plasma, and Serum Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>5. Quantification of Antidepressants Using Gas Chromatography-Mass Spectrometry</P>
<P>Ruth E. Winecker</P>
<P></P>
<P>6. Quantitation of Argatroban in Plasma using Liquid Chromatography Electrospray Tandem Mass Spectrometry (UPLC-ESI-MS/MS)</P>
<P>Ross J. Molinaro</P>
<P></P>
<P>7. Quantitation of Amobarbital, Butalbital, Pentobarbital, Phenobarbital, and Secobarbital in Urine, Serum, and Plasma Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Leonard L. Johnson and Uttam Garg</P>
<P></P>
<P>8. Quantitation of Benzodiazepines in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>9. LC-MS/MS Analysis of 13 Benzodiazepines and Metabolites in Urine, Serum, Plasma, and Meconium</P>
<P>Stephanie J. Marin and Gwendolyn A. McMillin</P>
<P></P>
<P>10. Simultaneous Determination and Quantification of 12 Benzodiazepines in Serum or Whole Blood Using UPLC/MS/MS</P>
<P>Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>11. Determination of Benzoic Acid in Serum or Plasma by Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Jeff M. Knoblauch, David K. Scott, Laurie D. Smith, and Uttam Garg</P>
<P></P>
<P>12. Quantification of Busulfan in Plasma Uing Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS)</P>
<P>Marion L. Snyder and James C. Ritchie</P>
<P></P>
<P>13. Quantitation of Total 11-Nor-9-Carboxy-Delta 9-Tetrahydrocannabinol in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>C. Clinton Frazee III, Michael Kiscoan, and Uttam Garg</P>
<P></P>
<P>14. Quantitation of Cocaine, Benzoylecgonine, Ecgonine Methyl Ester, and Cocaethylene in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Steven W. Fleming, Amitava Dasgupta, and Uttam Garg</P>
<P></P>
<P>15. Identification and Quantitation of Cocaine, Benzoylecgonine, and Cocaethylene in Blood, Serum, and Plasma Using Ultra-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry (UPLC-MS/MS)</P>
<P>Scott Kriger, Josh Gunn, and Andrea R. Terrell</P>
<P></P>
<P>16. Detection and Quantification of Cocaine and Benzoylecgonine in Meconium Using Solid Phase Extraction and UPLC/MS/MS</P>
<P>Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>17. Diagnosis of Creatine Metabolism Disorders by Determining Creatine and Guanidinoacetate in Plasma and Urine </P>
<P>Qin Sun and William E. O'Brien</P>
<P></P>
<P>18. Broad Spectrum Drug Screening Using Electron-Ionization Gas Chromatography-Mass Spectrometry (EI-GCMS)</P>
<P>Judy Stone</P>
<P></P>
<P>19. Broad Spectrum Drug Screening Using Liquid Chromatography-Hybrid Triple Quadrupole Linear Ion Trap Mass Spectrometry</P>
<P>Judy Stone</P>
<P></P>
<P>20. High Sensitivity Measurement of Estrone and Estradiol in Serum and Plasma Using LC-MS/MS </P>
<P>Mark M. Kushnir, Alan L. Rockwood, Bingfang Yue, and A. Wayne Meikle</P>
<P></P>
<P>21. 3-Hydroxy-Fatty Acid Analysis by Gas Chromatography-Mass Spectrometry </P>
<P>Patricia M. Jones and Michael J. Bennett</P>
<P></P>
<P>22. Quantitation of Fentanyl in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>23. Determination of Total Homocysteine in Plasma Using Liquid Chromatography Coupled to Tandem Mass Spectrometry (LC/MS/MS)</P>
<P>Bruno Casetta</P>
<P></P>
<P>24. Quantitation of Homovanillic Acid (HVA) and Vanillylmandelic Acid (VMA) in Urine Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Ryan Allenbrand and Uttam Garg</P>
<P></P>
<P>25. Quantitation of 17-OH-Progesterone (OHPG) for Diagnosis of Congenital Adrenal Hyperplasia (CAH)</P>
<P>Ravinder J. Singh</P>
<P></P>
<P>26. Determination of Hydroxyurea in Serum or Plasma Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>David K. Scott, Kathleen Neville, and Uttam Garg</P>
<P></P>
<P>27. Quantitation of Ibuprofen in Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Gerry Huber and Uttam Garg</P>
<P></P>
<P>28. Quantitation of Indomethacin in Serum and Plasma Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Sarah Thomas, Amanda Sutton, and Uttam Garg</P>
<P></P>
<P>29. Quantitation of Iothalamate in Urine and Plasma Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS)</P>
<P>Ross J. Molinaro and James C. Ritchie</P>
<P></P>
<P>30. Identification and Quantitation of Ketamine in Biological Matrices Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Timothy P. Rohrig, Megan Gamble,<SUP> </SUP>and Kim Cox</P>
<P></P>
<P>31. Measurement of Filter Paper Bloodspot Lead by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) </P>
<P>Denise M. Timko and Douglas F. Stickle</P>
<P></P>
<P>32. Multiplex Lysosomal Enzyme Activity Assay on Dried Blood Spots Using Tandem Mass Spectrometry</P>
<P>X. Kate Zhang, Carole S. Elbin, Frantisek Turecek, Ronald Scott, Wei-Lien Chuang, Joan M. Keutzer, and Michael Gelb</P>
<P></P>
<P>33. Gas Chromatography-Mass Spectrometry Method for the Determination of Methadone and 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP)</P>
<P>Christine L.H. Snozek, Matthew W. Bjergum, and Loralie J. Langman</P>
<P></P>
<P>34. Liquid Chromatography-Tandem Mass Spectrometry (LC-MSMS) Method for Monitoring Methotrexate in the Setting of Carboxypeptidase-G2 Therapy</P>
<P>Vikram S. Kumar, Terence Law, and Mark Kellogg</P>
<P></P>
<P>35. Quantitation of Methylmalonic Acid in Serum or Plasma Using Isotope Dilution-Selected Ion Gas Chromatography-Mass Spectrometry</P>
<P>Jie Chen and Michael J. Bennett</P>
<P></P>
<P>36. Quantitation of Methylmalonic Acid in Plasma Using Liquid Chromatography–Tandem Mass Spectrometry</P>
<P>Claudine Fasching and Jasbir Singh</P>
<P></P>
<P>37. Monitoring of Mycophenolate Acid in Serum or Plasma Using LC Tandem Mass Spectrometry</P>
<P>Catherine A. Hammett-Stabler, Diane Ciuffetti Geis, James Ritchie, and Christine Papadea</P>
<P></P>
<P>38. Quantitation of Nicotine, Its Metabolites, and Other Related Alkaloids in Urine, Serum, and Plasma Using LC-MS/MS</P>
<P>Bingfang Yue, Mark M. Kushnir, Francis M. Urry, and Alan L. Rockwood</P>
<P></P>
<P>39. Quantitation of Opioids in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>40. Quantitation of Morphine, Codeine, Hydrocodone, Hydromorphone, Oxycodone, Oxymorphone, and 6-Monoacetylmorphine (6-MAM) in Urine, Blood, Serum, or Plasma Using Liquid Chromatography with Tandem Mass Spectrometry Detection</P>
<P>Tim Dahn, Josh Gunn, Scott Kriger, and Andrea R. Terrell</P>
<P></P>
<P>41. Urine Organic Acid Analysis for Inherited Metabolic Disease Using Gas Chromatography-Mass Spectrometry</P>
<P>Patricia M. Jones and Michael J. Bennett</P>
<P></P>
<P>42. Identification of Urine Organic Acids for the Detection of Inborn Errors of Metabolism Using Urease and Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Stanley F. Lo,<SUP> </SUP>Velta Young, and William J. Rhead</P>
<P></P>
<P>43. Quantitation of Orotic Acid in Urine Using Isotope Dilution-Selected Ion Gas Chromatography-Mass Spectrometry</P>
<P>Jie Chen and Michael J. Bennett</P>
<P></P>
<P>44. Quantitation of Oxycodone in Blood and Urine Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Bruce A. Goldberger, Chris W. Chronister, and Michele L. Merves</P>
<P></P>
<P>45. Quantitation of Phencyclidine (PCP) in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Angela M. Ferguson and Uttam Garg</P>
<P></P>
<P>46. Quantitation of Sirolimus Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS)</P>
<P>Magdalena Korecka and Leslie M. Shaw</P>
<P></P>
<P>47. Quantitation of Tacrolimus in Whole Blood Using High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC/MS/MS)</P>
<P>Keri J. Donaldson and Leslie M. Shaw</P>
<P></P>
<P>48. Analysis of Testosterone in Serum Using Mass Spectrometry</P>
<P>Robert L. Fitzgerald, Terrance L. Griffin, and David A. Herold</P>
<P></P>
<P>49. Determination of Tetrahydrozoline in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC/MS)</P>
<P>Judy Peat and Uttam Garg</P>
<P></P>
<P>50. Quantitation of 25-OH-Vitamin D (25OHD) Using Liquid Tandem Mass Spectrometry (LC-MS/MS)</P>
<P>Ravinder J. Singh</P>
<P></P>
<P>51. Identification and Quantitation of Zolpidem in Biological Matrices Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Timothy P. Rohrig, Lydia A. Harryman, and Melissa C. Norton</P>
<P></P>
<P>52. Identification and Quantitation of Zopiclone in Biological Matrices Using Gas Chromatography-Mass Spectrometry (GC-MS)</P>
<P>Timothy P. Rohrig, Melissa C. Norton, and Lydia A. Harryman</P>