Cellular Senescence

Detecting Cellular Senescence in Reprogramming.- DNA Damage In situ Ligation followed by Proximity Ligation Assay (DI-PLA).- Reactive Oxygen Species Detection in Senescent Cells.- Cellular Identification and Quantification of Senescence-associated β-Galactosidase Activity in vivo.- Relative Human Telomere Length Quantification by Real-time PCR.- Assessing Functional Roles of the Senescence-associated Secretory Phenotype (SASP).- Measuring the Inflammasome in Oncogene-induced Senescence.- Alarmin Detection in Senescent Cells.- IMR90 ER:RAS: A Cell Model of Oncogene-induced Senescence.- Genotoxic Stress-induced Senescence.- A Multi-parametric Assay to Evaluate Senescent Cells.- A Novel Quantitative Method for the Detection of Lipofuscin, the Main Byproduct of Cellular Senescence, in Fluids.- Measurement of Metabolite Changes in Senescent Cells by Mass Spectrometry.- Quantification of Autophagy during Senescence.- Quantification of Aneuploidy in Mammalian Systems.- Identification of Genomic Alterations Through Multi-Level DNA Structural Analysis.- Mouse Models of Accelerated Cellular Senescence.- Methods to Quantify the NF-kB Pathway during Senescence.