Nicotinic Acetylcholine Receptor Technologies
Samenvatting
This volume provides properties, biological function, methods,
and approaches for manipulating nAChRs in different organisms. Nicotinic
Acetylcholine Receptor Technologies guides readers through molecular
techniques and behavioral tests used to investigate nicotinic drugs,
chronoamperometry, emerging technologies and methods for the analysis of
nAChRs, single nucleotide polymorphism (SNP), fluorescence techniques, spectral
confocal, allosteric modulators of a7-nAChRs, and a comprehensive evolutional
relation for most nAChR subunits, in both vertebrate and invertebrate species.
Written for the popular Neuromethods series, chapters include the
kind of detail and key implementation advice that ensures successful results in
the laboratory.
Authoritative and practical, Nicotinic Acetylcholine
Receptor Technologies aims to ensure successful results in the
further study of this vital field.
Specificaties
Inhoudsopgave
of Nicotinic Acetylcholine Receptor (nAChR) Gene Expression in the Zebrafish (Danio
rerio)by In Situ Hybridization and PCR.- Zebrafish:
An Animal Model to Study Nicotinic Drugs on Spatial Memory and Visual
Attention.- Conditioned
Place Preference and Behavioral Analysis to Evaluate Nicotine Reinforcement
Properties in Zebrafish.- Study of the
Contribution of Nicotinic Receptors to the Release of Endogenous Biogenic
Amines in Drosophila Brain.- Emerging Technologies
in the Analysis of C. Elegans Nicotinic
Acetylcholine Receptors.-
Using Natural Genetic
Variability in Nicotinic Receptor Genes to Understand the Function of Nicotinic
Receptors.- Nicotinic Acetylcholine Receptors as Targets
for Tobacco Cessation Therapeutics:
Cutting-edge Methodologies to Understand Receptor Assembly and
Trafficking.- Spectral Confocal Imaging to Examine Upregulation of
Nicotinic Receptor Subunits in α4-Yellow Fluorescent Protein Knock-in Mice.- α7-nicotinic
Acetylcholine Receptors: New Therapeutic Avenues in Alzheimer's Disease.-
α7-nicotinic Acetylcholine Receptors and β-amyloid Peptides in Alzheimer's
Disease.- Development
of Antidepressant Drugs Through Targeting a4β2-Nicotinic Acetylcholine
Receptors.- Evolutionary Relationship of Nicotinic Acetylcholine Receptor Subunits
in Both Vertebrate and Invertebrate Species. </p>