Urolithiasis

Clinical and Basic Research

Specificaties
Paperback, 1035 blz. | Engels
Springer US | 0e druk, 2013
ISBN13: 9781468489798
Rubricering
Springer US 0e druk, 2013 9781468489798
€ 122,99
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Samenvatting

In 1968 Drs. B. E. C. Nordin and A. Hodgkinson organized the First International Symposium on Urolithiasis Research in Leeds, England. One hundred and five participants from continental Europe, Great Britain, and the United States met to review their work and exchange ideas regarding the formation of urinary calculi. This meeting achieved several important goals. It pulled together a nidus of workers in the many scientific disciplines that relate to urolithiasis. This nidus served as the seed for research growth in a complex, interdisciplinary field. It established a forum for con­ tinuing communication in urolithiasis research with subsequent sym­ posia being held every 4 years. The Williamsburg Symposium was the fourth in the Leeds-Madrid­ Davos series involving 186 participants from throughout the world. A stated emphasis was on clinical research under way in the field. There were no invited speakers and for the first time the 41 papers that were presented orally at the meeting were selected from 184 submitted abstracts. A total of 134 papers were presented in the poster sessions in the afternoons where informal exchange between interested participants and investigators could occur without the restrictions of a plenary session. Virtually all areas of urolithi­ asis research from the most fundamental physical chemistry to clinical patterns of disease and specific modes of treatment were presented, reviewed and discussed during the meeting.

Specificaties

ISBN13:9781468489798
Taal:Engels
Bindwijze:paperback
Aantal pagina's:1035
Uitgever:Springer US
Druk:0

Inhoudsopgave

I. Clinical Urolithiasis.- Evaluation.- The Main Risk Factor for Calcium Oxalate Stone Disease in Man: Hypercalciuria or Mild Hyperoxaluria?.- Prediction of Stone Recurrence.- Crystalluria.- Study of Calcium Crystals in Patients with Kidney Stones.- Metabolic Investigations in 407 Recurrent Stone-Formers and Healthy Controls on Condition of Individual as well as Standard Diet.- Classification of Stone-Patients and Healthy Persons on the Basis of the Urinary Analysis.- Urinary Excretion of Citrate in Normal Subjects and Patients with Urolithiasis.- Magnesium Excretion in Urine on Condition of Individual as well as Standard Diet in Healthy Controls and Calcium Oxalate Stone-Formers.- Circadian Excretion of Uric Acid on Condition of Standard Diet after Purine Load in Calcium Oxalate Stone—Formers and Healthy Controls.- Hypophosphatemia in Recurrent Renal Stone—Formers — Consequence of Arterial Hypertension?.- Relationship of Urinary Calcium to Sodium Excretion in Calcareous Renal Stoneformers: Effect of Furosemide.- The Clinical Importance of Renal Tubular Acidosis in Recurrent Renal Stone Formers.- Experience with the Short Ammonium Chloride Test.- Urinary Excretion of Amino Acids by Subjects with Renal Calculi.- Excretion of the Ca—Binding Amino Acid, ?–Carboxyglutamate, in Stone—Formers.- Renal Stone Formation in Primary Hyperparathyroidism — Role of Tubular Dysfunction.- Short Ammonium Chloride Loading Test for Evaluation of Hyperparathyroidism.- Saturation of Urine in Primary Hyperparathyroidism: Its Role in Renal Stone Formation.- Clinical Disorders.- Medullary Sponge Kidney (Tubular Ectasia) in Calcium Urolithiasis.- Clinical and Laboratory Findings in Patients with Medullary Sponge Kidney.- Hereditary Hyperuricosuric Urolithiasis.- 2,8-Dihydroxyadeninuria: Or When is a Uric Acid Stone not a Uric Acid Stone?.- Renal Calculi in Triamterene Users.- Cystine Stone — Therapy with Alpha—Mereapto— Propionylglycine — Ten Years of Experience with Forty—Two Patients.- The Natural History of Cystinuria: A 15 Year Follow—Up in 106 Patients.- Glutamine Therapy of Cystinuria.- Urinary Stone Formation in Bowel Disease.- Prevalence of Nephrolithiasis in Malabsorptive Syndromes.- The Influence of Gastrointestinal Anatomy on Oxalate Excretion and Kidney Stone Incidence in Patients with Enteric Hyperoxaluria.- Therapy for Enteric Hyperoxaluria: A Comparison of Calcium Supplementation and Urinary Alkalinization.- Retrospective Follow—Up of Patients with Struvite Calculi.- Infected Renal Lithiasis: Results of Long—Term Surgical and Medical Management.- Infection—Induced Stones: Status of Clinic Trials with UrostatTM (Acetohydroxamic Acid).- Urease Inhibitors in the Treatment of Infection Induced Stones: Some Chemical, Pharmacologic and Clinical Considerations.- Complications and Management of “Neglected” Renal Stones.- Field Preventive Program of Bladder Stone Disease in Thailand.- Treatment.- Objective Evidence for the Beneficial Effect of a High Fluid Intake in the Management of Nephrolithiasis.- Reduction of Urinary Oxalate Excretion During Chronic Thiazide Therapy.- Long—Term Treatment with Bendroflumethiazide for Prevention of Renal Stones. Clinical Experiences.- Long—Term Treatment with Bendroflumethiazide for Prevention of Stones. Metabolic Effects.- Experiences with Thiazides in a Double Blind Study.- Neutral Potassium Phosphate and Thiazide: Combined Treatment in Recurrent Stone Formers.- Phosphate Treatment of Idiopathic Calcium Stone Disease.- Prophylactic Treatment with Magnesium Hydroxide in Renal Stone Disease.- Experiences with Long-Term Use of Sodium Cellulose Phosphate for Prevention of Renal Calcium Stones.- Long—Term Effects of Campanyl in the Treatment of Patients with Recurrent Calcium Urinary Stones.- How to Increase the Lithoprotective and/or Litholytic Properties of Urine.- Natural Volatile Oils in the Management of Renal Calcium Stone Disease.- Fybranta(R) — A New Approach to the Treatment of Idiopathic Hypercalciuria.- II. Epidemiology, Nutrition and Environment.- A Risk Factor Model of Stone-Formation: Application to the Study of Epidemiological Factors in the Genesis of Calcium Stones.- The Role of Affluence in Recurrent Stone Formation.- Alcohol as an Epidemiological Risk in Urolithiasis.- Familial Hypercalciuric Urolithiasis.- Cause of Primary Bladder Stone in England — A Retrospective Epidemiological Study.- Endemic Bladder Stones in Indonesia.- Future of Tamarind and Tartrate in Preventing Recurrence of Renal Calculi.- Dietary Structure and Urinary Composition in a Stone-Free Population.- Idiopathic Hypercalciuria — Its Control with Unprocessed Bran.- Urolithiasis — A Study of Drinking Water Hardness and Genetic Factors.- Urine Chemistry in Renal Stone-Formers in an Area with Soft Drinking Water.- The Importance of Chronic Cadmium Poisoning in Renal Stone Formation — A Five Year Study.- Should Recurrent Calcium Oxalate Stone Formers Eat Less Animal Protein?.- Influence of Purine Content of Diet and Allopurinol on Uric Acid and Oxalate Excretion Levels.- Increased Availability of Dietary Carbohydrate: A Factor in the Genesis of Idiopathic Calcium Oxalate Urolithiasis?.- Reduction of Urinary Oxalate Excretion in Primary Hyperoxaluria by Diet.- III. Crystal Formation and Physical Chemistry.- Preface on Standardized Nomenclature.- Paper on Standardized Nomenclature.- A Constant Composition Method for Modelling Urinary Stone Formation.- Crystal Growth and Aggregation of Calcium Oxalate in High Ionic Strength Solutions.- The Electrical Double Layer at Calcium Oxalate-Water Interfaces.- Calcium Electrode Measurements of Calcium Oxalate Mineralization: The Effects of Urine and Other Inhibitors.- Effect of Urinary Macromolecules on Calcium Oxalate Dihydrate Crystal Growth and Nucleation Rates.- Equilibrium-Based Computer Model for the Estimation of Urine Saturation.- The Relation Between Relative Supersaturation and Crystal Aggregation in Urine — An SEM Study and a Computerized Calculation of the Ion Equilibrium.- Determination of the Stability Constant of the Calcium Dioxalate Complex.- Calcium Oxalate Hydrates. Dissolution, Transformation and Crystallization Studies.- On the Transition Amorphous Calcium Phosphate to Crystalline Octacalcium Phosphate.- Stabilizing Factors for Uric Acid Dihydrate — A Contribution to Uric Acid Stone Formation.- Epitaxis Between Stone-Forming Crystals at the Atomic Level.- The Effect of Seed Crystals on Calcium Oxalate Nucleation.- The Effect of Urinary pH on the Saturation of Calcium and Oxalate and on Urinary Crystal Formation.- Hyperuricosuria in Calcium Oxalate Urolithiasis and its Possible Relationships with Stone Matrix Formation.- Calcium Oxalate Crystallization in Urothelial-Lined Systems.- Intrarenal Calcium and Oxalate Concentration Gradients in Healthy and Stone Forming Kidneys — The Renal Papilla as the Primary Nucleation Site.- Rat Renal Papillary Structure in Oxalate- Induced Microlithiasis, A Scanning Electron Microscope Study.- The Ultrastructure of Rat Renal Tubules in Experimental Calcium Oxalate Nephrolithiasis.- Crystal Formation in the Renal Tubules of Rats Induced by Ethylene Glycol Administration and Magnesium Deficiency.- A New View of Stone Formation Under the Aspect of Flow Dynamics.- Rates and Mechanisms of Dissolution of Renal Calculi. I. Rates and Mechanisms of Dissolution of Pure Calcium Oxalate Monohydrate in Acid and EDTA Solution.- Rates and Mechanisms of Dissolution of Renal Calculi. II. Development and Discussion of Potential Models for Dissolution of Oxalate Calculi.- Rates and Mechanisms of Dissolution of Renal Calculi. III. Mechanisms and Rates of Dissolution of Simulated Oxalate Calculi in Acid and EDTA Solutions.- IV. Inhibitors and Promoters.- Inhibition of PTH-Induced Nephrocalcinosis by Phosphocitrate.- The Sources of Phosphocitrate and its Role as an Inhibitor of Calcium Phosphate and Calcium Oxalate Crystallization.- Characterization of the Calcium Oxalate Crystal Growth Inhibitors in Human Urine.- Inhibitors of Calcium Oxalate and Calcium Phosphate Crystal Formation in Urine — A Critique and Reappraisal.- Studies on Inhibitors and Promoters of the Crystallization of Calcium Oxalate in Urine and in Matrix from Calcium Oxalate Stones.- Effect of Different Urinary Constituents on Inhibiting or Accelerating Calcium Oxalate Crystallization.- The Effect of Normal and Stone-Forming Urine on the Growth and Aggregation of Calcium Oxalate Crystals in Relation to Urinary Glycosaminoglycans and Urate Concentrations.- Urinary Glycosaminoglycan Excretion in Patients with Urolithiasis.- Inhibition of Calcium Oxalate Crystal Growth in Patients with Urolithiasis.- The Effect of Urine and Other Inhibitors on the Growth and Aggregation of Calcium Oxalate Crystals in Vitro.- Identification of a Small Molecular Weight Inhibitor of the Oxalate Precipitation.- The Effect of Some Urinary Constituents on the In Vitro Nucleation and Growth Kinetics of Calcium Oxalate.- Isolation of a Urinary Mucoprotein Capable to Precipitate Oxalate.- The Inhibitory Effect of Polymeric Carboxylic Amino-Acids and Urine on Calcium Oxalate Crystallization.- Inhibited Precipitation and Growth of Ca-Oxalate Crystals in the Presence of the Alkaline Salts of some Polyhydroxycarboxylic Acids.- Interaction of Dyes with Inorganic Constituents of Kidney Stones.- V. Matrix.- Urinary Calcium Binding Proteins and Renal Calculi.- Excretion of Tamm-Horsfall Urinary Glycoprotein (Uromucoid) in Renal Calcium Stone Formers.- Proteolytic Activity and Organic Substances in Urine.- Mechanism of the Heterogeneous Nucleation by a Urinary Mucoprotein.- Nephrolithiasis in Dialysed Patients — Evidence for a Peculiar Type of Matrix Stones with Ca-Oxalate Inclusions.- The Chemical Composition of a Non- Crystalline Feline Kidney Stone.- VI. Renal and Gastrointestinal Physiology.- The Effects of Chlorothiazide on Sodium, Calcium, and Magnesium Transport in the Nephron of the Thyroparathyroidectomized Hamster.- Indomethacin Lowers Urinary Calcium Excretion in Normal Volunteers and Normocalciuric Stone-Formers.- On the Mechanism of Action of l,25(OH)2D3 in the Intestine.- Low Phosphate Diet in Rats: A Model for Calcium Oxalate Urolithiasis.- Intracellular Mechanisms Underlying the Phosphaturie Response to Parathyroid Hormone in the Hamster.- Role of Nicotinamide Adenine Dinucleotide (NAD) in Control of Proximal Renal Tubular Phosphate Transport.- The Incidence of Nephrocalcinosis and the Urinary Excretion of Citrate and Calcium in Patients with Non-Azotemic Type 4 Renal Tubular Acidosis.- Urinary Citrate Excretion and Acidification Defects in Renal Calcium Stone Formers.- Influence of Changes in Calcium Metabolism on Renal Handling of Oxalate in Rats.- Evaluation of a New Oxalate Assay.- Intestinal Oxalate Absorption in Calcium Oxalate Stone Disease.- Oxalate Loading Test for the Diagnosis of Oxalate Hyperabsorption.- Effect of Vitamin B6 Deficiency on the Intestinal Absorption and Excretion of Oxalate in Rats.- Excretion of Oxalic Acid Following the Ingestion of Various Amounts of Oxalic Acid-Rich Foods.- Response of Gastrointestinal Hormones and Intestinal Calcium Absorption During an Oral Carbohydrate Meal.- How to Prevent the Hyperresorption of Dietary Oxalate and the Oxalate Peaks in Urine.- Isolation of the Oxalate Binding Protein.- VII. Metabolism.- The Pathophysiological Basis of Hypercalciuria in Primary Hyperparathyroidism.- Plasma 1,25(OH)2D in Idiopathic and Hyperparathyroid Stone-Formers.- Orthophosphate Therapy Decreases Urinary Calcium Excretion and Serum 1,25- Dihydroxy Vitamin D Concentrations in Idiopathic Hypercalciuria.- Cyclic Nucleotides and Related Variables in Urolithiasis.- Disturbed Terminal Mineralization of Bone in Idiopathic Hypercalciuria.- Dietary Calcium Restriction may be Good for Patients’ Stones — But not for Their Bones.- The Pathways of Oxalate Biosynthesis.- Alterations in Kidney Enzymes of Oxalate Metabolism in Patients with Urolithiasis.- Therapeutic Role of Vitamin B6 on Oxalate Metabolism in Urolithiasis and its Effect on Hyperoxaluria Induced in Rats by Ethylene Glycol.- Decomposition of Exogenous 14C-Oxalate (14C-OX) to l4C-Carbon Dioxide (14CO2) In Vitro and in Animals.- Enhancement of Urinary Citrate in Oxalate Stone Formers by the Intake of Alkaline Salts.- Magnesium Metabolism in Renal Stone Formers.- Urate Metabolism and Urinary Acidification.- Urate Metabolism in Calcium Stone Disease.- VIII. Stone Morphology and Structure.- Investigation with Polarizing Microscopy for the Classification of Urinary Stones From Humans and Dogs.- Statistical Results of the Analysis of more than 7,000 Urinary Calculi.- “Milk of Calcium”: Morphology, Structure, and Mineralogical Composition.- Oolitic Structure of Milk of Calcium Sand and Milk of Calcium Stones.- Silica in Urinary Calculi.- Newberyte in Old Renal and Bladder Calculi.- Forms of Ammonium Urate Presentation in Urinary Calculi of Non-Infectious and Infectious Origin.- Prostatic Calculi.- IX. Analytical Methods.- Isotachophoretic Determination of Oxalate in Unprocessed Urine.- Analytical Isotachophoresis: An Improved Method for Quantitative Determination of Urinary Oxalate.- The Effect of Storage on Seriun Oxalate Values.- Direct Measurement of Ionized Calcium (Standardization, Normal Values and Clinical Results).- New Glass Capillary Gas-Chromatographic Methods for Metabolites in Urine and Serum.- Comparison of X-ray Diffraction, IR-Spectroscopic, and Polarizing Microscopic Core-Shell Analysis of Urinary Stones.- Experience with Infrared Analysis of Urinary Tract Calculi in a Clinical Laboratory.- High Voltage Electron Microscopy of Urinary Calculi.- Physical Investigations of Urinary Calculi.- Investigations for Characterizing Single Crystal Phases in Urinary Stones by Means of an Arrangement of Light Microscopy in Combination with Scanning Microscopy.- List of Participants.
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        Urolithiasis