Naiara Rodríguez-Ezpeleta,
Michael Hackenberg,
Ana M. Aransay
Springer New York
2012e druk, 2011
9781461407812
Bioinformatics for High Throughput Sequencing
Specificaties
Gebonden, 255 blz.
|
Engels
Springer New York |
2012e druk, 2011
ISBN13: 9781461407812
Rubricering
Verwachte levertijd ongeveer 8 werkdagen
Samenvatting
Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.
Specificaties
ISBN13:9781461407812
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:255
Uitgever:Springer New York
Druk:2012
Inhoudsopgave
Preface.- Introduction.- Overview of Sequencing Technology Platforms.- Applications of High Throughput Sequencing.- Computational Infrastructure and Basic Data Analysis for High-Throughput Sequencing.- Base-Calling for Bioinformaticians.- De Novo Short Read Assembly.- Short Read Mapping.- DNA-Protein Interaction Analysis (ChIP-Seq).- Genome-wide Methylation Maps.- Differential Expression for RNA Sequencing (RNA-seq) Data: Mapping, Summarization, Statistical Analysis and Experimental Design.- MicroRNA Expression Profiling and Discovery.- Dissecting Splicing-Regulatory Network by Integrative Analysis of HITS-CLIP data.- Analysis of Metagenomics Data.- High Throughput Sequencing Data Analysis Software: Current State and Future Developments.- Index.