Part I: Purine Metabolism in the Heart 1. Physiologic and Pathophysiologic Significance of Purine Metabolism in the Heart; A.-S.A. Abd-Elfattah, et al. 2. Purine Metabolism in the Ischemic Canine and Human Immature Myocardium Deficient of 5¿-Nucleotidase; A.- S.A. Abd-Elfattah, et al. 3. Cardiac Adenosine Metabolism: Physiological Implications; A. Deusson. 4. Purines Metabolism in Human Cardiomyocytes and Endothelium-Implications for Protection of the Heart during Cardiac Surgery; R.T. Smolenski, M. Yacoub. 5. Assessment of Interstitial Fluid Adenosine: Implications for Exogenous or Endogenous and Endogenous Adenosine-Mediated Cardioprotection; D.G.L. Van Wylen. 6. Adenosine and Coronary Vascular Pharmacology; W. Abebe, et al. 7. Alternations in Energy Substrate Metabolism during Oxidative Stress; A.S. Clanachan, Gary Lopaschuck. Part II: Myocardial Protection with Purines. 8. Purines and Myocardial Protection: An Overview; A.-S.A. Abd-Elfattah, et al. A. Myocardial Protection with Endogenous Purines. 9. Nucleoside Transport Protein: Properties and Regulation; A.-S.A. Abd-Elfattah, et al. 10. Role of Nucleoside Transport in Myocardial Injury and Protection: Separation Between Ischemic and Reperfusion Injury using a Selective Nucleoside Transport Blocker, NBMPR; A.-S.A. Abd-Elfattah, et al. 11. Myocardial Protection using Nucleoside Transport Inhibitors; H. Van Belle. 12. Selective Blockade of Nucleoside Transport by NBMPR Attenuates Reperfusion-Mediated Ventricular Arrhythmias; A.-S.A. Abd-Elfattah, et al. 13. NucleosideTransport in the Human Myocardium; J. Hoehner, et al. 14. Selective Nucleoside Transport Blocker NBMPR Attenuates Myocardial Stunning in a Rabbit Mode- Deficient of Xanthine Oxidase; A.-S.A. Abd-Elfattah, et al. 15. Amplification of Endogenous Adenosine by `Adenosine Regulating Agents' as a Therapeutic Approach to the Treatment of Cardiac Ischemic Syndromes; K. Mullane, et al. B. Myocardial Protection with Exogenous Purines. 16. Organ Protection with ATP-Magnesium Chloride; J.M. Harkema, I.H. Chaudry. 17. Adenosine and Adenosine Receptor Protection of the Ischemic Heart; R.D. Lasely, R.J. Mentzer, Jr. 18. Effect of Adenosine on Myocardial Stunning; M. Jerudi, et al. 19. Cardioprotection with Adenosine, inosine and Hypoxanthine; J.W. de Jong, et al. 21. Adenosine and Adrenergic Mediated Effects in the Heart; J.G. Dobson, Jr. 22. Effects of Adenosine on Ventricular Tachycardia; A. Pelleg, J. Xu. 23. Purines and Ventricular Arrhythmias; R. Fenton. 24. Adenosine and the Polymorphonuclear Leukocyte Function, Metabolism and Production; B. Cornstein. 25. Purines and Regulation of Platelet Activation; K. Agrwal. Part III: Purines and Myocardial Preconditioning. 26. Myocardial Preconditioning: From a Model to a Phenomenon; A.-S. Abd-Elfattah, et al. 27. ATP Metabolism and Ischemic Preconditioning; K.A. Reimer, et al. 28. Do Adenosine A3 Receptors Cause Preconditioning? J.M. Downey, et al. 29. KATP Channels and Adenosine Receptors and Ischemic