Hector R. Wong,
Thomas Shanley
Springer US
0e druk, 2012
9781461355489
Molecular Biology of Acute Lung Injury
Specificaties
Paperback, 329 blz.
|
Engels
Springer US |
0e druk, 2012
ISBN13: 9781461355489
Rubricering
Onderdeel van serie
Molecular & Cellular Biology of Critical Care Medicine
Levertijd ongeveer 8 werkdagen
Samenvatting
Acute lung injury (ALI) impacts patient care in every ICU in the world. Our collective understanding of this condition has grown immensely over the past decade but morbidity and mortality remain unacceptably high. To enhance the understanding of clinicians and researchers, this book addresses the pathophysiology of acute lung injury from a molecular and cellular standpoint; includes animal models of acute lung injury and points to potential therapeutic advances based on scientific findings. It is a concise compendium of the multiple pathways, mechanisms and molecules involved in the pathophysiology of acute lung injury and is intended to help caregivers understand the process and thus care for patients more effectively.
Specificaties
ISBN13:9781461355489
Taal:Engels
Bindwijze:paperback
Aantal pagina's:329
Uitgever:Springer US
Druk:0
Inhoudsopgave
1. Signal Transduction Pathways in Acute Lung Injury: NF-?B and AP-1.- 2. Innate Immune Mechanisms Triggering Lung Injury.- 3. The Role of Chemokines in the Recruitment of Leukocytes During Lung Inflammation.- 4. Regulation of Lung Immunity: Significance of the Cytokine Environment.- 5. Role of Complement in Acute Lung Injury.- 6. Oxidant Stress in Acute Lung Injury.- 7. Endogenous Nitric Oxide in Acute Lung Injury.- 8. Heme Oxygenase-1 in Acute Lung Injury.- 9. Pulmonary Endothelial Surface Redox Activity: Roles in Propagation of and Protection from Injury.- 10. Mechanisms of Lung Epithelial Cell Injury by Pseudomonas Aeruginosa.- 11. Alveolar Epithelial Repair in Acute Lung Injury.- 12. Molecular Basis for Surfactant Function in ARDS.- 13. Pulmonary Collectins and Defensins.- 14. Lung Repair, Remodeling, and Fibrosis.- 15. Apoptosis in Acute Lung Injury.- 16. Corticosteroid Treatment in Unresolving ARDS.- 17. Anti-inflammatory Cytokines: Role in Regulation of Acute Lung Injury.- 18. The Heat Shock Response and Heat Shock Protein 70: Cytoprotection in Acute Lung Injury.- 19. Biotrauma: Signal Transduction and Gene Expression in the Lung.