The Superficial Dorsal Horn.- The Superficial Dorsal Horn.- Section I: Afferent Inputs to the Superficial Dorsal Horn.- Distribution of unmyelinated primary afferent fibres in the dorsal horn.- Spinal projections of thin myelinated deep afferents and their topical relation to dorsal horn neurones processing deep input.- The distribution of muscle and cutaneous projections to the dorsal horn of the upper cervical cord of the cat.- Electron microscopic localization of peptide-like immunoreactivity in labelled dorsal root terminals in the spinal substantia gelatinosa of the monkey.- Immunoreactivity of rat primary afferent neurones with C- and A- fibres.- Coexistence of peptides in primary afferent neurones.- Laminar and segmental termination in the dorsal horn of the spinal cord of an articular nerve of the forepaw in the cat.- Spinal termination of primary afferents of the cat’s knee joint.- Cell size and Nissl pattern analyses of primary afferent neurons innervating the molar tooth pulp and cornea of the rat.- Visceral and somatic afferent origin of calcitonin gene-related peptide-immunoreactivity in the superficial and deep laminae of the thoracic spinal cord of the rat.- Discussion.- Section II: Receptive Field Properties of Lamina I Neurons.- Characterization of lamina I projection neurons: physiology and anatomy.- Input to and output from lamina I neurones in the cat spinal cord.- The influence of cutaneous inputs on the activity of neurones in the substantia gelatinosa.- Superficial dorsal horn neurons in the rat responsive to visceral and cutaneous inputs.- Identification of a sub-population of viscero-somatic neurones unique to the superficial dorsal horn.- Discussion.- Section III: Spinal and Supraspinal Outputs from the Superficial Dorsal Horn.- Characterization of long ascending tract projection neurons and non-tract neurons in the superficial dorsal horn (SDH).- Projections and neurochemical specificity of the different morphological types of marginal cells.- Projections of the superficial dorsal horn to the midbrain and thalamus.- Discussion.- Section IV: Development and Plasticity in the Superficial Dorsal Horn.- The significance of plastic changes in lamina 1 systems.- Molecular events in the spinal cord following sensory stimulation.- Denervation induced changes in somatotopic organization: the ineffective projections of afferent fibres and structural plasticity.- Physiological and pharmacological induction of c-fos protein immunoreactivity in superficial dorsal horn neurones.- Modality properties and inhibitory receptive fields of dorsal horn neurones in cats with dorsolateral funiculus lesions.- Discussion.- Section V: Neurotransmitters and Peptides in the Superficial Dorsal Horn.- Glutamate and other putative mediators of fast synaptic action in the superficial dorsal horn.- Peripheral stimuli releasing neuropeptides in the dorsal horn of the cat.- Somatic, articular and visceral noxious-stimulus-evoked expression of c-fos in the spinal cord of the rat: differential patterns of activity and modulation by analgesic agents.- In situ hybridization histochemical and immunocytochemical analysis of opioid gene products in a rat model of peripheral inflammation.- In vitro studies on neurones of the superficial dorsal horn in slices of 9–16 day old rat spinal cord.- Opioid and serotonergic effects on lamina I and deeper dorsal horn neurones.- Discussion.- Section VI: Superficial Dorsal Horn Changes Following Peripheral Injury.- Opioid receptors in the dorsal horn of intact and deafferented rats: autoradiographic and electrophysiological studies.- Neuronal plasticity in the superficial dorsal horn following peripheral tissue inflammation and nerve injury.- Afferent induced alterations of receptive field properties.- Neurochemical and anatomical changes in the dorsal horn of rats with an experimental, painful peripheral neuropathy.- A comparison of the receptive field plasticity of nocireceptive and multireceptive dorsal horn neurones following noxious mechanical stimulation.- Discussion.- Section VII: Effects of Technical Approaches on Current Opinions about the Superficial Dorsal Horn.- What modulates tonic modulation of spinal dorsal horn neurons?.- On the influence of anaesthesia, stimulus intensity and drug access in pharmacological tests of sensory processing in the superficial dorsal horn.- Discussion.- List of Participants.- Author Index.
