Periodontal Medicine and Systems Biology
Samenvatting
This book provides a systems–based approach to periodontology and offers a scientific roadmap of the interactions which can lead to periodontal disease.
Specificaties
Inhoudsopgave
<p>Contributors.</p>
<p>PART I SYSTEMS THEORY AND COOPERATIVE BACTERIA.</p>
<p>1 Systems thinking in biology (Robert M. Seymour).</p>
<p>2 Metagenomics and its applications to human bacterial diseases (Julian R. Marchesi).</p>
<p>PART II PERIODONTITIS: THE CLINICAL DISEASE.</p>
<p>3 Periodontitis: a modern clinical picture (Nikos Donos and Francesco D Aiuto).</p>
<p>4 Plaque microbiology in (periodontal) health and disease (Anne D. Haffajee).</p>
<p>5 Population molecular genetics of periodontitis (Marja L. Laine, Ubele van der Velden and Bruno G. Loos).</p>
<p>6 Mechanisms linking periodontitis to systemic disease (Panos N. Papapanou and Jan H. Behle).</p>
<p>7 The impact of diabetes–enhanced inflammation on periodontal disease and bone destruction (Dana T. Graves).</p>
<p>PART III PERIODONTITIS: COPINGWITH THE MICROBIOTA.</p>
<p>8 The microbiota of humans (Gerald W. Tannock).</p>
<p>9 The normal oral microbiota (William G. Wade).</p>
<p>10 Bacterial coaggregation and periodontitis (Paul E. Kolenbrander, Natalia I. Chalmers, Saravanan Periasamy, A.M. Ding and Shayla L. West–Barnette).</p>
<p>11 Dynamics of biofilm formation and relationship to periodontitis (Jonathan Pratten and Nicola Mordan).</p>
<p>12 Quorum sensing as a means of biofilm communication (Hanjuan Shao and Donald R. Demuth).</p>
<p>13 Genomics of Porphyromonas gingivalis (Keisuke Nakayama).</p>
<p>14 Genomics of Fusobacterium nucleatum (Vinayak Kapatral).</p>
<p>15 The Aggregatibacter (formerly Actinobacillus) actinomycetemcomitans genome annotation, analysis and metabolic reconstruction (Fares Najar, Shaoping Lin, Lin Song, Hongshing Lai, James White, Steven Kenton and Bruce A. Roe).</p>
<p>PART IV PERIODONTITIS: INNATE AND ACQUIRED IMMUNITY.</p>
<p>16 A new view of innate immunity for the twenty–first century (John Wright and Clare E. Bryant).</p>
<p>17 Innate immunity and homeostasis in the periodontium (Richard P. Darveau).</p>
<p>18 Antimicrobial host defence peptides in oral health and periodontitis (Deirdre A. Devine and Celine Cosseau).</p>
<p>19 Control of inflammation in periodontal disease (Hatice Hasturk, Alpdogan Kantarci and Thomas E. Van Dyke).</p>
<p>20 Antigen–presenting cells in chronic periodontitis (Ravi Jotwani and Christopher W. Cutler).</p>
<p>21 B–cell responses in periodontitis (Suzanne E. Barbour, John G. Tew and Harvey A. Schenkein).</p>
<p>22 T–cell responses in periodontitis (Gregory J. Seymour, Erica Gemmell and Kazuhisa Yamazaki).</p>
<p>PART V PERIODONTITIS: BONE DESTRUCTION.</p>
<p>23 Current paradigms of osteoblast osteoclast interactions and bacterial pathogen–induced bone resorption (Naoyuki Takahashi, Masanori Koide, Toshihide Noguchi and Tatsuo Suda).</p>
<p>24 Bacterial osteolytic mediators (Brian Henderson and Sean P. Nair).</p>
<p>25 Immune cell involvement in periodontal bone loss (Andy Y.–T. Teng).</p>
<p>26 How can periodontal bone loss be stopped? (Colin R. Dunstan).</p>
<p>Index.</p>