The Greening of Pharmaceutical Engineering – Theories and Solutions v2

<p>Preface ix</p>
<p>1 Introduction 1</p>
<p>1.1 Opening Statement 1</p>
<p>1.2 The Way Out: How Do We Make Use of Existing Knowledge? 1</p>
<p>1.3 The Driver of The Knowledge Model 3</p>
<p>1.4 The Proof of The Pudding is in The Eating! 7</p>
<p>1.5 The Proof is in The Pudding 8</p>
<p>1.6 Summary of Introduction 9</p>
<p>2 Nature–Science Approach: Some Further Consequences 11</p>
<p>2.1 Cognitive Dissonance 11</p>
<p>2.1.1 Summary Remarks about Theories that Disconnect Conscience from Humanity 11</p>
<p>2.2 Foods for Thought 12</p>
<p>2.2.1 Artificial Food Addiction 12</p>
<p>2.2.2 Organic and Mechanical Frequencies 13</p>
<p>2.3 Example from CCD Analysis 17</p>
<p>2.4 A New Approach to Product Characterization 22</p>
<p>2.5 A New Paradigm 25</p>
<p>2.5.1 Violation of Characteristic Time 25</p>
<p>2.5.2 Observation of Nature: Importance of Intangibles 25</p>
<p>2.5.3 Analogy of Physical Phenomena 28</p>
<p>2.5.4 Intangible Cause to Tangible Consequence 28</p>
<p>2.5.5 Removable Discontinuities: Phases and Renewability of Materials 30</p>
<p>2.5.6 Redefining Force and Energy 37</p>
<p>2.5.6.1 Force 37</p>
<p>2.5.6.2 Energy 38</p>
<p>2.6 What is a Natural Energy Source? 42</p>
<p>2.7 The Science of Water and Oil 47</p>
<p>2.7.1 Comparison between Water and Petroleum 50</p>
<p>2.7.2 Combustion and Oxidation 65</p>
<p>2.7.3 Natural Energy vs. Artificial Energy 67</p>
<p>2.8 From Natural Energy to Natural Mass 72</p>
<p>2.9 Avalanche Theory of Mass and Energy 98</p>
<p>2.10 Aims of Modeling Natural Phenomena 106</p>
<p>2.11 Simultaneous Characterization of Matter and Energy 108</p>
<p>2.12 Implications 110</p>
<p>2.13 Consequences of Nature–Science for Classical Set Theory and Conventional Notions of Mensuration 114</p>
<p>2.14 Conclusions 116</p>
<p>2.14.1 Need for a Change 116</p>
<p>2.14.2 The Nature Science Approach 117</p>
<p>3 A Knowledge–Based Cognition Model 119</p>
<p>3.1 Abstract 119</p>
<p>3.2 Introduction 120</p>
<p>3.3 The Current Cognitive Model 125</p>
<p>3.3.1 Policy–Making and The Aphenomenal Model 126</p>
<p>3.3.2 The Aphenomenal Model in Science 132</p>
<p>3.3.2.1 Example 1: Aphenomenal Time Function 134</p>
<p>3.3.3 Fear and Perception 148</p>
<p>3.4 What is Human Thought Material (HTM)? 151</p>
<p>3.5 Knowledge through Experience or Delinearized History? 154</p>
<p>3.6 HTM from The Standpoint of Nature–Science 156</p>
<p>3.6.1 Cognition with Conscious and Conscientious Participation 156</p>
<p>3.7 The Basic Quantum of HTM 157</p>
<p>3.8 Freedom of Intention 169</p>
<p>3.8.1 The Knowledge–Based Cognition Process 171</p>
<p>3.9 Conclusions 177</p>
<p>4 Implications of a Comprehensive Material Balance Equation for Detecting Causes of Medical Disorders 179</p>
<p>4.1 Summary 179</p>
<p>4.2 Introduction 180</p>
<p>4.3 Paradox and New Science 183</p>
<p>4.3.1 Obesity Paradox 184</p>
<p>4.3.2 Obesity/Mortality Paradox 184</p>
<p>4.3.3 Simpson s Paradox 184</p>
<p>4.3.4 Low Birth Weight Paradox 187</p>
<p>4.3.5 Prevention Paradox 188</p>
<p>4.3.6 The Novelty Paradox 189</p>
<p>4.3.7 The Paradox of Worsening Conditions With Medications 190</p>
<p>4.3.8 The Prostate Paradox 192</p>
<p>4.3.9 The Health–Lifespan Paradox 192</p>
<p>4.3.10 Smoker s Paradox 193</p>
<p>4.3.11 Paradox of The Natural 193</p>
<p>4.3.12 The French Paradox 194</p>
<p>4.3.13 Paradox of Aging 194</p>
<p>4.3.14 Paradox of Translational Medicine 194</p>
<p>4.3.15 Peto s Paradox 195</p>
<p>4.3.16 TGF– Paradox 195</p>
<p>4.3.17 Hispanic Paradox 195</p>
<p>4.4 Origin of Paradox: Implication of Probability Assumptions 196</p>
<p>4.4.1 Probability of Creation and Life 199</p>
<p>4.5 A Word About Inductive and Conductive Rules 201</p>
<p>4.6 Deconstructing Game Theory 208</p>
<p>4.6.1 Impact of The Deliberate Hunger Game 226</p>
<p>4.6.2 The Prisoner s Dilemma 237</p>
<p>4.7 Towards Explaining Phenomena 253</p>
<p>4.7.1 Blood–Brain Barrier and Cancer 253</p>
<p>4.7.2 New Drug that Works on Cells that Mutate Faster and Works on Smokers 254</p>
<p>4.7.3 Wireless Energy Transfer 256</p>
<p>4.7.4 Curing Colorblindness 258</p>
<p>4.7.5 Surgical Intervention Recapitulating the HSSA Model 260</p>
<p>4.7.6 Editing Embryo: To Engineer or Not to Engineer 264</p>
<p>4.7.7 From Original Sin to Original Lunacy 265</p>
<p>4.7.8 Teenagers Heavy Pot Smoking Tied to Memory Problems (or How Many Angels can Dance on the Head of a Pin Updated) 268</p>
<p>4.7.9 Cigarettes Even a Fetus can Tell What s Harmful 269</p>
<p>4.7.10 Water, or: Commodification of The Most Abundant Fluid on EarTh271</p>
<p>4.7.11 Accelerating in Reverse 273</p>
<p>4.7.12 Recycling The Hunger Games Mantra 276</p>
<p>4.7.13 The Ultimate of Original Sin 278</p>
<p>4.7.14 Fifteen Immune–System Boosting Foods (via WebMD) 282</p>
<p>4.7.14.1 Elderberry 282</p>
<p>4.7.14.2 Acai Berry 282</p>
<p>4.7.14.3 Oysters 282</p>
<p>4.7.14.4 Watermelon 283</p>
<p>4.7.14.5 Cabbage 283</p>
<p>4.7.14.6 Almonds 283</p>
<p>4.7.14.7 Grapefruit 283</p>
<p>4.7.14.8 Wheat Germ 283</p>
<p>4.7.14.9 Low–Fat Yogurt 283</p>
<p>4.7.14.10 Garlic 284</p>
<p>4.7.14.11 Spinach 284</p>
<p>4.7.14.12 Tea 284</p>
<p>4.7.14.13 Sweet Potato 284</p>
<p>4.7.14.14 Broccoli 284</p>
<p>4.7.14.15 Button Mushrooms 284</p>
<p>4.7.15 OK for Food But Not Pets? 285</p>
<p>5 Conclusion and Recommendation 287</p>
<p>5.1 The Importance of Being Earnest About</p>
<p>Cognition versus Perception 287</p>
<p>5.2 HSSAN Degradation 288</p>
<p>5.3 Greening of Pharmaceutical Industry 289</p>
<p>5.3.1 Phases of Life 289</p>
<p>5.3.2 Recognize The Stimulant 290</p>
<p>5.3.3 Remove Negative Stimulant in Order to</p>
<p>Reverse The Symptoms 290</p>
<p>5.3.4 Replacement of Artificial with Natural 291</p>
<p>5.3.5 Medicines and Therapies with Natural Substitutes 291</p>
<p>5.3.6 Mental Conditioning and Staged Prevention 291</p>
<p>References and Bibliography 295</p>
<p>Appendix 319</p>
<p>Index 353</p>