HN Shah
John Wiley & Sons
e druk, 2017
9781118960257
MALDI–TOF and Tandem MS for Clinical Microbiology
Specificaties
Gebonden, 648 blz.
|
Engels
John Wiley & Sons |
e druk, 2017
ISBN13: 9781118960257
Rubricering
Levertijd ongeveer 15 werkdagen
Samenvatting
This book highlights the triumph of MALDI–TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI–TOF MS. Chapters discuss:
Challenges of Identifying Mycobacterium to the Species level
Identification of Bacteroides and Other Clinically Relevant Anaerobes
Identification of Species in Mixed Microbial Populations
Detection of Resistance Mechanisms
Proteomics as a biomarker discovery and validation platform
Determination of Antimicrobial Resistance using Tandem Mass Spectrometry
Specificaties
Inhoudsopgave
<p>List of Contributors xxi</p>
<p>Preface xxix</p>
<p>Part I MALDI–TOF Mass Spectrometry 1</p>
<p>1 A Paradigm Shift from Research to Front ]Line Microbial Diagnostics in MALDI ]TOF and LC ]MS/MS: A Laboratory s Vision and Relentless Resolve to Help Develop and Implement This New Technology amidst Formidable Obstacles 3<br />Haroun N. Shah and Saheer E. Gharbia</p>
<p>2 Criteria for Development of MALDI ]TOF Mass Spectral Database 39<br />Markus Kostrzewa and Thomas Maier</p>
<p>3 Applications of MALDI ]TOF Mass Spectrometry in Clinical Diagnostic Microbiology 55<br />Onya Opota, Guy Prod hom and Gilbert Greub</p>
<p>4 The Challenges of Identifying Mycobacterium to the Species Level using MALDI ]TOF MS 93</p>
<p>5 Transformation of Anaerobic Microbiology since the Arrival of MALDI ]TOF Mass Spectrometry 123<br />Elisabeth Nagy, Mariann Abrok, Edith Urban, A.C.M. Veloo, Arie Jan van Winkelhoff, Itaru Dekio, Saheer E. Gharbia and Haroun N. Shah</p>
<p>6 Differentiation of Closely Related Organisms using MALDI ]TOF MS 147<br />Mark A. Fisher</p>
<p>7 Identification of Species in Mixed Microbial Populations using MALDI ]TOF MS 167<br />Pierre Mahe, Maud Arsac, Nadine Perrot, Marie ]Helene Charles, Patrick Broyer, Jay Hyman, John Walsh, Sonia Chatellier, Victoria Girard, Alex van Belkum, and Jean ]Baptiste Veyrieras</p>
<p>8 Microbial DNA Analysis by MALDI ]TOF Mass Spectrometry 187</p>
<p>9 Impact of MALDI ]TOF MS in Clinical Mycology; Progress and Barriers in Diagnostics 211<br />Cledir R. Santos, Elaine Francisco, Mariana Mazza, Ana Carolina B. Padovan, Arnaldo Colombo and Nelson Lima</p>
<p>10 Development and Application of MALDI ]TOF for Detection of Resistance Mechanisms 231<br />Stefan Zimmermann and Irene Burckhardt</p>
<p>11 Discrimination of Burkholderia Species, Brucella Biovars, Francisella tularensis and Other Taxa at the Subspecies Level by MALDI ]TOF Mass Spectrometry 249<br />Axel Karger</p>
<p>12 MALDI ]TOF ]MS Based on Ribosomal Protein Coding in S10 ]spc ]alpha Operons for Proteotyping 269<br />Hiroto Tamura</p>
<p>Part II Tandem MS/MS–Based Approaches to Microbial Characterization 311</p>
<p>13 Tandem Mass Spectrometry Analysis as an Approach to Delineate Genetically Related Taxa 313<br />Raju V. Misra, Tom Gaulton, Nadia Ahmod, Min Fang, Martin Hornshaw, Jenny Ho, Saheer E. Gharbia and Haroun N. Shah</p>
<p>14 Mapping of the Proteogenome of Clostridium difficile Isolates of Varying Virulence 379<br />Caroline H. Chilton, Saheer E. Gharbia, Raju V. Misra, Min Fang, Ian R. Poxton, Peter S. Borriello and Haroun N. Shah</p>
<p>15 Determination of Antimicrobial Resistance using Tandem Mass<br />Spectrometry 399<br />Ajit J. Shah, Vlad Serafim, Zhen Xu, Hermine Mkrtchyan and Haroun N. Shah</p>
<p>16 Proteotyping: Tandem Mass Spectrometry Shotgun Proteomic Characterization and Typing of Pathogenic Microorganisms 419<br />Roger Karlsson, Lucia Gonzales ]Siles, Fredrik Boulund, Asa Lindgren, Liselott Svensson ]Stadler, Anders Karlsson, Erik Kristiansson and Edward R.B. Moore</p>
<p>17 Proteogenomics of Pseudomonas aeruginosa in Cystic Fibrosis Infections 451<br />Liang Yang and Song Lin Chua</p>
<p>18 Top ]Down Proteomics in the Study of Microbial Pathogenicity 493<br />Joseph Gault, Egor Vorontsov, Mathieu Dupre, Valeria Calvaresi, Magalie Duchateau, Diogo B. Lima, Christian Malosse and Julia Chamot ]Rooke</p>
<p>19 Tandem Mass Spectrometry in Resolving Complex Gut Microbiota Functions 505<br />Carolin Kolmeder, Kaarina Lahteenmaki, Pirjo Wacklin, Annika Kotovuori, Ilja Ritamo, Jaana Matto, Willem M. de Vos, and Leena Valmu</p>
<p>20 Proteogenomics of Non ]model Microorganisms 529<br />Jean Armengaud</p>
<p>21A Analysis of MALDI ]TOF MS Spectra using the BioNumerics Software 539<br />Katleen Vranckx, Katrien De Bruyne and Bruno Pot</p>
<p>21B Subtyping of Staphylococcus spp. Based upon MALDI ]TOF MS Data Analysis 563<br />Zhen Xu, Ali Olkun, Katleen Vranckx, Hermine V. Mkrtchyan, Ajit J. Shah, Bruno Pot, Ronald R. Cutler and Haroun N. Shah</p>
<p>21C Elucidating the Intra ]Species Proteotypes of Pseudomonas aeruginosa from Cystic Fibrosis 579<br />Ali Olkun, Ajit J. Shah and Haroun N. Shah</p>
<p>References 588</p>
<p>Index 593</p>
<p> </p>
<p>Preface xxix</p>
<p>Part I MALDI–TOF Mass Spectrometry 1</p>
<p>1 A Paradigm Shift from Research to Front ]Line Microbial Diagnostics in MALDI ]TOF and LC ]MS/MS: A Laboratory s Vision and Relentless Resolve to Help Develop and Implement This New Technology amidst Formidable Obstacles 3<br />Haroun N. Shah and Saheer E. Gharbia</p>
<p>2 Criteria for Development of MALDI ]TOF Mass Spectral Database 39<br />Markus Kostrzewa and Thomas Maier</p>
<p>3 Applications of MALDI ]TOF Mass Spectrometry in Clinical Diagnostic Microbiology 55<br />Onya Opota, Guy Prod hom and Gilbert Greub</p>
<p>4 The Challenges of Identifying Mycobacterium to the Species Level using MALDI ]TOF MS 93</p>
<p>5 Transformation of Anaerobic Microbiology since the Arrival of MALDI ]TOF Mass Spectrometry 123<br />Elisabeth Nagy, Mariann Abrok, Edith Urban, A.C.M. Veloo, Arie Jan van Winkelhoff, Itaru Dekio, Saheer E. Gharbia and Haroun N. Shah</p>
<p>6 Differentiation of Closely Related Organisms using MALDI ]TOF MS 147<br />Mark A. Fisher</p>
<p>7 Identification of Species in Mixed Microbial Populations using MALDI ]TOF MS 167<br />Pierre Mahe, Maud Arsac, Nadine Perrot, Marie ]Helene Charles, Patrick Broyer, Jay Hyman, John Walsh, Sonia Chatellier, Victoria Girard, Alex van Belkum, and Jean ]Baptiste Veyrieras</p>
<p>8 Microbial DNA Analysis by MALDI ]TOF Mass Spectrometry 187</p>
<p>9 Impact of MALDI ]TOF MS in Clinical Mycology; Progress and Barriers in Diagnostics 211<br />Cledir R. Santos, Elaine Francisco, Mariana Mazza, Ana Carolina B. Padovan, Arnaldo Colombo and Nelson Lima</p>
<p>10 Development and Application of MALDI ]TOF for Detection of Resistance Mechanisms 231<br />Stefan Zimmermann and Irene Burckhardt</p>
<p>11 Discrimination of Burkholderia Species, Brucella Biovars, Francisella tularensis and Other Taxa at the Subspecies Level by MALDI ]TOF Mass Spectrometry 249<br />Axel Karger</p>
<p>12 MALDI ]TOF ]MS Based on Ribosomal Protein Coding in S10 ]spc ]alpha Operons for Proteotyping 269<br />Hiroto Tamura</p>
<p>Part II Tandem MS/MS–Based Approaches to Microbial Characterization 311</p>
<p>13 Tandem Mass Spectrometry Analysis as an Approach to Delineate Genetically Related Taxa 313<br />Raju V. Misra, Tom Gaulton, Nadia Ahmod, Min Fang, Martin Hornshaw, Jenny Ho, Saheer E. Gharbia and Haroun N. Shah</p>
<p>14 Mapping of the Proteogenome of Clostridium difficile Isolates of Varying Virulence 379<br />Caroline H. Chilton, Saheer E. Gharbia, Raju V. Misra, Min Fang, Ian R. Poxton, Peter S. Borriello and Haroun N. Shah</p>
<p>15 Determination of Antimicrobial Resistance using Tandem Mass<br />Spectrometry 399<br />Ajit J. Shah, Vlad Serafim, Zhen Xu, Hermine Mkrtchyan and Haroun N. Shah</p>
<p>16 Proteotyping: Tandem Mass Spectrometry Shotgun Proteomic Characterization and Typing of Pathogenic Microorganisms 419<br />Roger Karlsson, Lucia Gonzales ]Siles, Fredrik Boulund, Asa Lindgren, Liselott Svensson ]Stadler, Anders Karlsson, Erik Kristiansson and Edward R.B. Moore</p>
<p>17 Proteogenomics of Pseudomonas aeruginosa in Cystic Fibrosis Infections 451<br />Liang Yang and Song Lin Chua</p>
<p>18 Top ]Down Proteomics in the Study of Microbial Pathogenicity 493<br />Joseph Gault, Egor Vorontsov, Mathieu Dupre, Valeria Calvaresi, Magalie Duchateau, Diogo B. Lima, Christian Malosse and Julia Chamot ]Rooke</p>
<p>19 Tandem Mass Spectrometry in Resolving Complex Gut Microbiota Functions 505<br />Carolin Kolmeder, Kaarina Lahteenmaki, Pirjo Wacklin, Annika Kotovuori, Ilja Ritamo, Jaana Matto, Willem M. de Vos, and Leena Valmu</p>
<p>20 Proteogenomics of Non ]model Microorganisms 529<br />Jean Armengaud</p>
<p>21A Analysis of MALDI ]TOF MS Spectra using the BioNumerics Software 539<br />Katleen Vranckx, Katrien De Bruyne and Bruno Pot</p>
<p>21B Subtyping of Staphylococcus spp. Based upon MALDI ]TOF MS Data Analysis 563<br />Zhen Xu, Ali Olkun, Katleen Vranckx, Hermine V. Mkrtchyan, Ajit J. Shah, Bruno Pot, Ronald R. Cutler and Haroun N. Shah</p>
<p>21C Elucidating the Intra ]Species Proteotypes of Pseudomonas aeruginosa from Cystic Fibrosis 579<br />Ali Olkun, Ajit J. Shah and Haroun N. Shah</p>
<p>References 588</p>
<p>Index 593</p>
<p> </p>