Posttraumatic Stress Disorder – From Neurobiology to Treatment
From Neurobiology to Treatment
Samenvatting
Posttraumatic Stress Disorder: From Neurobiology to Treatment presents a comprehensive look at this key neuropsychiatric disorder. The text examines the neurobiological basis of post–traumatic stress and how our understanding of the basic elements of the disease have informed and been translated into new and existing treatment options.
The book begins with a section on animal models in posttraumatic stress disorder research, which has served as the basis of much of our neurobiological information. Chapters then delve into applications of the clinical neuroscience of posttraumatic stress disorder. The final part of the books explores treatments and how our basic and clinical research is now being converted into treatment. Taking a unique basic science to translational intervention approach,
Posttraumatic Stress Disorder: From Neurobiology to Treatment is an invaluable resource for researchers, students and clinicians dealing with this complex disorder.
Specificaties
Inhoudsopgave
<p>Introduction, xi</p>
<p>Section I: Preclinical sciences of stress</p>
<p>1 Posttraumatic stress disorder: from neurobiology to clinical presentation 3<br /> Arieh Y. Shalev & J. Douglas Bremner</p>
<p>2 The epidemiology of posttraumatic stress disorder in children and adolescents: a critical review 27<br /> Leah A. McGuire</p>
<p>3 Early life stress and development: preclinical science 61<br /> Dora B. Guzman, Brittany Howell & Mar Sanchez</p>
<p>4 Amygdala contributions to fear and safety conditioning: insights into PTSD from an animal model across development 81<br /> Christopher Cain & Regina Sullivan</p>
<p>5 Preclinical evidence for benzodiazepine receptor involvement in the pathophysiology of PTSD, comorbid substance abuse, and alcoholism 105<br /> Robert Drugan, Nathaniel P. Stafford & Timothy A. Warner</p>
<p>6 Psychosocial predator stress model of PTSD based on clinically relevant risk factors for trauma–induced psychopathology 125<br /> Phillip R. Zoladz & David Diamond</p>
<p>7 Coping with stress in wild birds the evolutionary foundations of stress responses 145<br /> Molly J. Dickens & Michael Romero</p>
<p>8 Stress, fear, and memory in healthy individuals 159<br /> Christian J. Merz, Bernet M. Elzinga & Lars Schwabe</p>
<p>Section II: Neurobiology of PTSD</p>
<p>9 Neurotransmitter, neurohormonal, and neuropeptidal function in stress and PTSD 181<br /> J. Douglas Bremner & Brad Pearce</p>
<p>10 Genomics of PTSD 233<br /> Anthony S. Zannas, Elisabeth Binder & Divya Mehta</p>
<p>11 Cortisol and the Hypothalamic Pituitary Adrenal Axis in PTSD 265<br /> Amy Lehrner, Nicolaos Daskalakis & Rachel Yehuda</p>
<p>12 Neuroimaging of PTSD 291<br /> Carolina Campanella & J. Douglas Bremner</p>
<p>Section III: PTSD and co–occuring conditions</p>
<p>13 PTSD and mild traumatic brain injury 321<br /> J. Douglas Bremner</p>
<p>14 Stress–related psychopathology and pain 345<br /> Sarah C. Reitz, Karl–Juergen Bär & Christian Schmahl</p>
<p>15 Stress and health 361<br /> Viola Vaccarino, Emeran Mayer & J. Douglas Bremner</p>
<p>Section IV: PTSD: from neurobiology to treatment</p>
<p>16 Pharmacotherapy for PTSD: effects on PTSD symptoms and the brain 389<br /> Lori Davis, Mark Hamner & J. Douglas Bremner</p>
<p>17 Effects of psychotherapy for psychological trauma on PTSD symptoms and the brain 413<br /> J. Douglas Bremner & Carolina Campanella</p>
<p>Index 421</p>