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Folate and Human Development

Specificaties
Gebonden, 359 blz. | Engels
Humana Press | 2002e druk, 2002
ISBN13: 9780896039360
Rubricering
Humana Press 2002e druk, 2002 9780896039360
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

An authoritative panel of basic and clinical researchers critically reviews the latest findings on the role of folate in human development, health, and disease. Specific areas addressed include folate metabolism in zinc or copper deficiencies, choline and folate in development, animal models of folate-related birth defects, developmental toxicants potentially acting via folate perturbation, and folate's role in vascular disease in women. There are also cutting-edge discussions of genes and neural tube development, folate receptor polymorphism and the risk for neural defects, abnormal DNA synthesis and methylation with folate/methyl insufficiency, and folic acid and homocysteine as risk factors for neural tube defects.

Specificaties

ISBN13:9780896039360
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:359
Uitgever:Humana Press
Druk:2002

Inhoudsopgave

Animal Models of Folate-Related Neural Tube Defects
Nicholas D. E. Greene and Andrew J. Copp

Genetic Variation in Folate Metabolism: Impact on Development
Rima Rozen

Folate Deficiency and the Molecular Determinants of Chromosome Instability: Possible Link to Meiotic Nondisjunction and Down Syndrome
S. Jill James and Charlotte A. Hobbs

Folic Acid, Vitamin B12, and Genomic Stability of Human Cells
Michael Fenech

Molecular Genetics of Folate Metabolism
Manuela Födinger, Sonja Skoupy, and Gere Sunder-Plassmann

Folate Receptor-a: An Update
Barton A. Kamen

Folate, Homocysteine, and Neural Tube Defects
Tom K. A. B. Eskes

Folic Acid and Homocysteine as Risk Factors for Neural Tube Defects
Robert C. Barber, Janée van Waes, Edward J. Lammer, Gary M. Shaw, Thomas H. Rosenquist, and Richard H. Finnell

Developmental Toxicants Potentially Acting via Folate Perturbation
Deborah K. Hansen

Brain Development and Choline, the Other Methyl Donor
Steven H. Zeisel

Nutrient Interactions Between Folate and Zinc or Copper: Their Possible Implications to Pregnancy Outcome
Tsunenobu Tamura

Regulation of Folate Metabolism by Iron
A. Katherine Herbig and Patrick J. Stover

A Differential Role for Folate in Developmental Disorders, Vascular Disease, and Other Clinical Conditions: The Importance of Folate Status and Genotype
Mark Lucock and Zoe Yates

Vascular Disease in Women: Folate and Homocysteine
Tom K. A. B. Eskes

Folate, Homocysteine, and Cardiovascular Disease
Jayne V. Woodside and Ian S. Young

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        Folate and Human Development