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Kratom

History, Science and Therapeutic Potential

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2025
ISBN13: 9780443274121
Rubricering
Elsevier Science e druk, 2025 9780443274121
Verwachte levertijd ongeveer 8 werkdagen

Samenvatting

Kratom: History, Science and Therapeutic Potential is the first book to address the unregulated, widespread availability of kratom, with its weak opioid and stimulant effects, coupled with limited awareness of it by healthcare professionals. Kratom has great therapeutic utility and medicinal potential, but more study, caution, and possible regulation is needed. It discusses geographical sourcing, historical uses, current worldwide uses, and potential for treatment of other medical conditions. Most exciting for healthcare professionals will be the implications of this substance's potential for treatment of diseases like depression, ADHD, PTSD, and substance-use disorder, particularly opioid use disorder (OUD).

Moreover, kratom and its active alkaloid mitragynine are getting remarkable attention at federal and local governments as more than eight million Americans consume this product annually. Yet, the paucity of information for researchers and clinicians is troublesome.

Specificaties

ISBN13:9780443274121
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

Section 1: Background<br>1. Botany, geographical distribution, and phytochemistry of Mitragyna speciosa (Korth.) and related species<br>Satya Swathi Nadakuduti, Mengzi Zhang, Larissa C. Laforest and Brian Pearson<br>2. The scientific evolution of kratom: a historical overview<br>Thiruventhan Karunakaran, Yathindra Marimuthu, Balasingam Vicknasingam and Marek C. Chawarski<br>3. Recent patterns and reasons for use<br>Marc T. Swogger, Kirsten E. Smith, Tianna Torrice and Oliver Grundmann<br>Section 2: Basic science<br>4. Chemistry and metabolites: ADME<br>Manoj Gundeti, Christopher R. Mccurdy and Abhisheak Sharma<br>Section 3: Current therapeutic uses<br>5. Kratom-related physical dependence and addiction<br>Kirsten E. Smith, Darshan Singh and Oliver Grundmann<br>6. Current therapeutic uses<br>Norsyifa Harun, Siti Rafidah Yusof and Farah Wahida Suhaimi<br>Section 4: Pharmaceutical drug development of kratom-derived products<br>7. Regulation and policy regarding kratom-derived dietary supplements and direct-to-consumer sales<br>Robert Durkin, Oliver Grundmann and Kirsten E. Smith<br>8. Patentability and exclusivity of kratom based natural products<br>Robert Paradiso<br>Section 5: Concerns<br>9. Kratom drug–drug (and other) interactions<br>Robert B. Raffa and Jeanette Mathews<br>10. Susceptible populations<br>Robert B. Raffa and Jeanette Mathews<br>Section 6: Commentaries/Perspectives<br>11. Kratom purity and quality control issues: an in-depth analysis<br>Frank Breve<br>12. Kratom entrepreneurship | exploiting the commercial potential of kratom and its active alkaloids<br>Chad E. Beyer<br>13. Equity investment into kratom, mitragynine, and related products<br>Zachariah Mcintosh-Pearce<br>14. Medical marijuana as a template for understanding kratom<br>Soren Shade

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        Kratom