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Microarrays

Preparation, Microfluidics, Detection Methods, and Biological Applications

Specificaties
Gebonden, 356 blz. | Engels
Springer New York | 2009e druk, 2008
ISBN13: 9780387727165
Rubricering
Springer New York 2009e druk, 2008 9780387727165
Onderdeel van serie Integrated Analytical Systems
Verwachte levertijd ongeveer 8 werkdagen

Samenvatting

Combinatorial chemistry is used to find materials that form sensor microarrays. This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions, peptide chemistry, carbodhydrate chemistry, electrochemical detection, and microfluidics.

Specificaties

ISBN13:9780387727165
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:356
Uitgever:Springer New York
Druk:2009

Inhoudsopgave

Overview and New Detection Method.- The Current Status of DNA Microarrays.- Electrochemical Detection on Microarrays.- Fluidic Manipulation and Microarrays.- Fully Integrated Microfluidic Device for Direct Sample-to-Answer Genetic Analysis.- Integrated Microfluidic Devices for Automated Microarray-Based Gene Expression and Genotyping Analysis.- Statistical Data Evaluation on Microarrays.- Intensity Concentration Relationships for Electrochemical Detection.- Applications.- Genotyping Arrays.- Peptide-Based Microarray.- Protein Microarrays for the Detection of Biothreats.- Photo-Generation of Carbohydrate Microarrays.- Expression Profiling Using Microfluidic Living Cell Arrays.- New Approaches to the Synthesis of Addressable Microarray Molecular Libraries.- eSensor®A Microarray Technology Based on Electrochemical Detection of Nucleic Acids and Its Application to Cystic Fibrosis Carrier Screening.- Future Improvements in Microarray Sensing.- Use of Redox Enzymes for the Electrochemical Detection of Sequence-Specific DNA and Immunochemical Entities.- Biochip Platforms for DNA Diagnostics.- MagArray Biochips for Protein and DNA Detection with Magnetic Nanotags: Design, Experiment, and Signal-to-Noise Ratio.- Bar Coding Platforms for Nucleic Acid and Protein Detection.- Electrochemical Nanoparticle-Based Sensors.

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