Physical Aspects of Hyperthermia.- Hyperthermia, Physics, Vector Potential, Electromagnetic Heating.- Thennometry.- Physical Background and Technical Realizations of Hyperthermia.- Thermotherapy and Nanomedicine.- Biological Aspects of Hyperthermia.- Influence of Tumor Microenvironment on Thermoresponse.- Hyperthermia and Angiogenesis.- Vascular Meets of Localized Hyperthermia.- On the Biochemical Basis of Tumour Damage by Hypothermia.- Results of Hyperthermia Alone or with Radiation Therapy and/or Chemotherapy.- Thermo-Chemo-Radiotherapy Association.- A Step Deep on Hyperthermia, Hypoxia and Chemotherapy Interactions.- Clinical Aspects of Hyperthermia.- Locoregional Hyperthermia.- Hyperthermia and Radiotherapy in the Management of Prostate Cancer.- Tumor Ablation Using Radiofrequency Energy.- Cytoreduction, Peritonectomy and Hyperthermic Antiblastic Peritoneal Perfiision for the Treatment of Peritoneal Carcinomatosis.- Hyperthermic Isolated Limb Perfusion.- Intracavitary Hyperthennic Perfusion.- Whole Body Hypothermia at 43.5–44°C.- Extreme Whole-Body Hyperthermia with Water-Filtered Infrared-A Radiation.- Effects of Local and Whole Body Hyperthermia on Immunity.- Fever, Pyrogens and Cancer.- Future Perspectives of Interstitial and Perfusional Hyperthermia.