Model-Assisted Bayesian Designs for Dose Finding and Optimization

Features

Represents the first book to provide comprehensive coverage of model-assisted designs for various types of dose-finding and optimization clinical trials

Describes the up-to-date theory and practice for model-assisted designs

Presents many practical challenges and issues arising from early-phase clinical trials

Illustrates with many real trial applications

Offers numerous tips and guidance on designing dose finding and optimization trials

Provides step-by-step illustration of using software to design trials

Develops a companion website (www.trialdesign.org) to provide easy-to-use software to assist learning and implementing model-assisted designs.