Notes on the Contributors General Introduction PART 1: TOOLS AND RESEARCH MATERIALS, THE INDUSTRIALIST AS PRODUCER Introduction Part 1 An Old Hand in a New System: Brewing Culture in Jame's Joule Heat Measurements; H. Sibum Sealing Wax and Strings, Plasticine and Valves: Industry, Instrumentation and the Emergence of Nuclear Physics; J. Hughes Instrument Hierarchies: Laboratories, Industry and Divisions of Labour; T. Shinn Theory from Practice: Portraying the Constitution of Synthetic Dyestuffs in the 1860s; T. Travis Can it Ever be Pure Science? Pharmaceuticals, the Pharmaceutical Industry, and Biomedical Research in the 20th Century; J. Goodman PART 2: STANDARDIZING TOOLS, OPERATORS AND PRACTICE: THE INDUSTRIALIST AS REGULATOR Introduction Instruments, Scientists, Industrialists and the Specificity of Influence: The Case of RCA and Biological Electron Microscopy; N. Rasmussen Disciplining Cancer: Mice and the Practice of Genetic Purity - Ilana Lowy & Jean-Paul Gaudilliere Interlaboratory Life: Regulating Flow Cytometry; Peter Keating & Alberto Cambrosio PART 3: ORGANIZATION OF RESEARCH AND POLICY: THE INDUSTRIALIST AS MANAGER Introduction Industrial R&D and Its Influence on the Organisation and Management of the Production of Knowledge in the Public Sector; V. Walsh Shifting Boundaries between Industry and Science: the Role of WHO in Contraceptive R&D; N. Oudshoorn Index