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Mechanisms of Morphogenesis

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2023
ISBN13: 9780323999656
Rubricering
Elsevier Science e druk, 2023 9780323999656
€ 171,40
Levertijd ongeveer 8 werkdagen

Samenvatting

Mechanisms of Morphogenesis, Third Edition offers a bottom-up discussion of mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. Across foundational, applied and methods-based chapters, this book examines molecular nano-machines cooperation, generate cell shape, direct cell migration, and shape, form and rates of growth of various tissues in the body. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and likely future developments, along with strategies to apply basic morphogenesis science across ever evolving applications.

Newly added chapters feature case-study-driven discussions of morphogenesis in natural embryos and organoids, and illustrate how pathological morphogenesis can generate variants of body form. This edition has also been updated with analysis of large-scale and scale-invariant mechanisms, for example, morphogenesis by differential growth in mechanically connected tissues.

Specificaties

ISBN13:9780323999656
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>Section I: Introduction<br>1. General introduction – the aims and structure of this book.<br>2. Key principles of morphogenesis<br>3. The power and limitations of self-assembly</p> <p>Section II: Cell shape and the cell morphogenesis<br>4. Morphogenesis of individual cells<br>5. Animal cell shape: the importance of the cytoskeleton<br>6. Cellular morphogenesis in plants</p> <p>Section III: Cell Migration<br>7. Cell migration in development: a brief overview<br>8. The nanomachinery of locomotion<br>9. Guidance by chemotaxis<br>10. Guidance by galvanotaxis<br>11. Guidance by contact<br>12. Waypoint navigation in the embryo<br>13. Cooperative migration of mesenchymal cells<br>14. Condensation of cells</p> <p>Section IV: Epithelial Morphogenesis<br>15. The epithelial state: a brief overview<br>16. Neighbour exchange and convergent extension<br>17. Closure of holes<br>18. Invagination and evagination<br>19. Epithelial fusion<br>20. Epithelial branching<br>21. Boundaries to epithelial movement</p> <p>Section V: Morphogenesis by cell proliferation and death <br>22. Growth, proliferation and death: a brief overview<br>23. Morphogenesis by orientated cell division<br>24. Morphogenesis by elective cell death</p> <p>Section VI: Morphogenesis in context<br>25. From mechanisms to morphology: a brief overview<br>26. Morphogenesis in embryos: some illustrative examples<br>27. Morphogenesis in organoids, embryoids and engineered tissues<br>28. Pathological morphogenesis</p> <p>Section VII: Modelling morphogenesis <br>29. Modelling morphogenesis: a brief overview<br>30. Mechanical and mathematical models of morphogenesis<br>31. Modelling using living cells – tissue engineering and synthetic morphology</p> <p>Section VIII: Conclusion and perspectives<br>32. Conclusion and perspectives</p>
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        Mechanisms of Morphogenesis