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HIV-Associated Neurocognitive Disorders

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2024
ISBN13: 9780323997447
Rubricering
Elsevier Science e druk, 2024 9780323997447
€ 265,00
Levertijd ongeveer 8 werkdagen

Samenvatting

HIV-Associated Neurocognitive Disorders (HAND) presents a complex and evolving challenge in the context of HIV-1 infection and treatment. This comprehensive volume dives into the clinical manifestations, molecular and cellular mechanisms, and therapeutic strategies underlying HAND and its associated comorbidities. This book brings together cutting-edge research and clinical insights, making it an essential resource for researchers, clinicians, and students engaged in HIV-related studies and neurocognitive research. This resource also aims to advance our understanding of HAND to contribute to the development of novel diagnostic tools and therapeutic interventions for improved patient outcomes.

Specificaties

ISBN13:9780323997447
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

1. An overview of the mechanisms of HIV-1 infection, latency, pathogenesis, and eradication strategies from the CNS<br>2. Central Nervous System Complications of Human Immunodeficiency Virus Infection<br>3. Health LIteracy in HIV-associated Neurocognitive Disorders<br>4. Neuroimaging insights into the CNS effects of HIV infection<br>5. Early and upstream subcellular organellar events associated with HAND<br>6. White matter loss and oligodendrocyte dysfunction in HAND<br>7. Pathogenesis of HIV-associated pain<br>8. Neuropathogenesis of HIV-associated neuropathic pain<br>9. Neuropathic Pain in HIV and the role of the Autophagy pathway<br>10. Host peripheral immune dynamics increase HIV-associated neurocognitive disorders incidence and progression<br>11. The role of immunometabolism in HIV associated depression and cognitive impairment<br>12. Role of extracellular viral regulatory proteins in neuropathogenesis<br>13. Role of inflammasomes in HIV-1 and drug abuse-mediated neuroinflammation<br>14. The Contribution of Myeloid Cells to HIV Neuropathogenesis<br>15. Immunophilin ligands modulate phagocytosis and viral replication in HIV-infected macrophages<br>16. Immunometabolic mechanisms of HIV-associated neurocognitive disorders and traumatic brain injury: Commonalities and contrasts between chronic and acute neurodegenerative pathologies<br>17. Endolysosome dysfunction in HAND<br>18. Evolving biomarkers for HIV-associated neurocognitive disorders (HAND)<br>19. Intracellular immunity against HIV infection<br>20. NeuroHIV and the Glymphatic System<br>21. The p75 neurotrophin receptor: emerging role in the pathogenesis of mature synapses in Human Immunodeficiency Virus-Associated Neurocognitive Disorders<br>22. The Role of HIV-Associated Neuroendocrine Dysfunction in HAND<br>23. Impact of SARS-CoV-2/COVID-19 on HIV-1-associated neurocognitive disorders<br>24. Molecular mechanisms of dopaminergic transmission in NeuroHIV<br>25. The effect of substance misuse on HIV persistence in the CNS: epidemiological, immunological, and molecular considerations<br>26. Extracellular vesicles in alcohol- and tobacco-induced neuroAIDS<br>27. NeuroHIV in the context of opioid use disorder: A complex and evolving relationship<br>28. Impairment of cholesterol homeostasis induced by Nef-containing extracellular vesicles as a factor in HAND pathogenesis<br>29. Long noncoding RNAs in immune response, viral infection, and opioid use<br>30. Using cross-species behavioral tools to determine mechanisms contributing to HIV associated neurological disorders and comorbid substance use<br>31. Therapeutic potential of Curcumin in treating HIV-1 associated neurocognitive disorders<br>32. Targeting the Endocannabinoid System in HAND<br>33. Predicting the effectiveness of combination treatment of Dolutegravir and Fluoxetine for Depressive disorders in HIV<br>34. ANTIRETROVIRAL THERAPY AND ITS CEREBRAL VASCULAR TOXICITY<br>35. Strategies for HIV-1 Elimination
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        HIV-Associated Neurocognitive Disorders