Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease

<p>Section I. Biophysical and Technical Principles<br>1. Basic Principles of pulsatile pressure and flow phenomena in elastic vessels<br>2. Measurements of arterial pressure and flow in vivo<br>3. Essential Principles of Pulsatile Pressure-flow relations in the arterial tree<br>4. Magnetic Resonance Imaging for the assessment of aortic stiffness and pulsatile hemodynamics<br>5. Computed tomography of the aorta<br>6. Radionuclide-based Imaging of the aortic wall<br>7. Arterial wall stiffness: basic principles and methods of measurement in vivo<br>8. Ambulatory measurements of pulsatile hemodynamics<br>9. Animal Models and Ex-vivo Methods to Study Arterial Stiffness</p> <p>Section II. Basic and Applied Physiology<br>10. Hemodynamic role of the Aorta<br>11. Wave Reflections in the arterial tree<br>12. Linking Arterial Stiffness to Microvascular Remodeling<br>13. Myocardial function: from myofilaments to cardiac pump<br>14. Systolic-diastolic coupling<br>15. Ventricular-arterial coupling: The pressure-volume plane<br>16. Myocardial wall stress and the systolic loading sequence<br>17. Assessment of Ventricular Arterial Interactions via arterial pressure-flow relations in humans<br>18. Hemodynamic Determinants of Myocardial Oxygen Demand and Supply</p> <p>Section III. Biologic pathways leading to arterial stiffness and dysfunctional pulsatile hemodynamics<br>19. Role of elastin and elastin-derived peptides in arterial stiffness: from synthesis to potential therapeutic interventions<br>20. Inflammation and arterial stiffness<br>21. Mechanisms of Aortic Wall Calcification<br>22. Vascular smooth muscle dysfunction and arterial stiffness<br>23. Endothelial cell dysfunction and Senescence: Biologic mechanisms and Hemodynamic consequences<br>24. Autonomic and neuroendocrine modulation of arterial stiffness and hemodynamics<br>25. Cellular mechanisms of ageing and their impact on the aortic/arterial wall</p> <p>SECTION IV. Clinical significance of arterial stiffness and pulsatile hemodynamics<br>26. Normal Aging: Arterial Stiffness and remodeling over the life course<br>27. Early Vascular Aging and Supernormal Vascular Aging: Genetics, Epigenetics, and Environment<br>28. Ethnic differences in arterial stiffness and central aortic hemodynamics<br>29. Arterial Stiffness and Pulsatile hemodynamics in Systemic Hypertension<br>30. Arterial Stiffness and Pulsatile hemodynamics in Diabetes and Obesity<br>31. Cardiovascular Risk Prevention in Clinical Practice: Current Guidelines in the USA and Europe<br>32. Cardiovascular Risk Prevention in Clinical Practice: Current Guidelines in Asia<br>33. Arterial Stiffness, Cardiovascular Risk and Strategies for enhancing risk Stratification<br>34. Role of the arterial tree in Physiologic Adaptations to exercise<br>35. Invasive Hemodynamic Assessments during exercise: Normal patterns and clinical value<br>36. Arterial Stiffness and Pulsatile hemodynamics in Heart Failure with Reduced and Preserved Ejection Fraction<br>37. Ventricular-Arterial Coupling and Arterial Load in Aortic Valvular Disease<br>38. Arterial Stiffness and Atherosclerosis: Mechanistic and Pathophysiologic Interactions<br>39. Arterial Stiffness and Pulsatile hemodynamics in Coronary Artery Disease and other forms of Atherosclerotic vascular diseases<br>40. Arterial Stiffness and Pulsatile hemodynamics in Renal disease<br>41. Arterial Stiffness, Pulsatile hemodynamics, Cognitive dysfunction<br>42. Arterial Stiffness and Pulsatile hemodynamics in pregnancy and pregnancy-related vascular complications <br>43. Arterial Stiffness and Pulsatile Hemodynamics in Pediatric populations<br>44. Aortopathies and Arteriopathies<br>45. Pulsatile hemodynamics and arterial stiffness in primary aortopathies<br>46. Arterial Hemodynamics and Pulsatile Hemodynamics in Congenital Heart Disease<br>47. Arterial Stiffness and Pulsatile Hemodynamics in Acute and Chronic Infectious Diseases<br>48. Arterial Stiffness, Hemodynamics and Microvascular Complications in conditions characterized by low arterial pulsatility</p> <p>SECTION V. Therapeutic approaches to improve arterial stiffness and pulsatile hemodynamics<br>49. Effects of common antihypertensive treatments on pulsatile arterial hemodynamics<br>50. Pharmacologic approaches to reduce arterial stiffness<br>51. Organic and dietary nitrates, inorganic nitrite, NO donors, and sGC stimulation<br>52. Effect of Exercise Training and Weight Loss on Arterial Stiffness and Pulsatile Hemodynamics<br>53. Dietary Salt and Arterial Stiffness<br>54. Role of Arterial Stiffness and Central Hemodynamics in Personalized medicine in hypertension</p> <p>Section VI. Arterial Stiffness and Pulsatile Hemodynamics in the Pulmonary Circulation<br>55. Pulsatile hemodynamics and Ventricular-Arterial Interactions in the pulmonary circulation: Physiologic Concepts<br>56. Pulmonary arterial load and its impact on the right ventricle in pulmonary hypertension<br>57. Biologic mechanisms and consequences of pulmonary artery stiffening in Pulmonary Hypertension<br>58. Therapeutic approaches to improve right ventricular load</p>