Handbook of Animal Models in Neurological Disorders

Section 1: Alzheimer’s Disease and Dementias<br>1. Caenorhabditis elegans model of Alzheimer's disease: applications to drug screening<br>2. APPswe/ PS1dE9 mouse model of Alzheimer’s disease: [18F]-florbetaben pet/ct imaging and beyond<br>3. Rat model of Alzheimer: applications to brain a-beta plaque accumulation<br><br>Section 2: Amyotrophic Lateral Sclerosis<br>4. Murine modelling of familial amyotrophic lateral sclerosis, SOD1G86R: applications to ambroxol HCl<br>5. Rat Model of amyotrophic lateral sclerosis: SOD1G93A applications to mitochondria<br>6. Zebrafish model of amyotrophic lateral sclerosis: applications to oxidative stress studies in spinal motor neurons<br><br>Section 3: Brain Injury<br>7. Murine models of traumatic brain injury and knock outs: investigations on hypocretin<br>8. Rat model of cortical impact traumatic brain injury: applications to studying neural stem cell grafts<br>9. Porcine modelling of traumatic brain injury: investigating agents such as valproic acid and beyond<br><br>Section 4: Cerebral Palsy<br>10. Animal models of cerebral palsy: a new narrative<br>11. Rat model of cerebral palsy: applications to studying motor phenotype<br>12. Rabbit cerebral palsy modelling: applications to studying spinal hyper-excitability<br><br>Section 5: Epilepsy<br>13. Murine modelling of epilepsy: applications to microRNA and hippocampus<br>14. Kainic acid-induced rat model of status epilepticus: A gamma-aminobutyric acid levels<br>15. Rats modelling of temporal lobe epilepsy: linking in cognition<br><br>Section 6: Headaches and Migraines<br>16. A new narrative of genetic mouse models of migraine: features and applications<br>17. Rat model of headache with nitroglycerin: impact of auricular electrical stimulation<br>18. Nitroglycerin-induced migraine in mice: Nociceptin Opioid (NOP) receptors and beyond<br><br>Section 7: Meningitis Rabbit tuberculous meningitis models: applications to neurosciences<br>19. Experimental pneumococcal meningitis: hippocampal DNA methylation<br>20. Pneumococcal meningitis modelling in mice<br><br>Section 8: Multiple Sclerosis Biological models in multiple sclerosis: a new overview and narrative<br>21. The mouse model of multiple sclerosis : use of Artemisia dracunculus L.<br>22. Comparing models of multiple sclerosis: applications to biomarkers<br><br>Section 9: Neuroinflammation Modelling neuroinflammation: CXCR2 signalling and myelin repair<br>23. Lipopolysaccharide- model of neuroinflammation: astrogliosis, microglial activation and beyond<br>24. Rat model of neuroinflammation: positron emission tomography (PET) tracer for imaging of P2X7 receptors<br><br>Section 10: Neurotoxins Animal models in the neurotoxicology of the neurotoxin 2,4-D<br>25. Toluene as a model neurotoxin in mouse models 1-11-2019<br>26. Rat model of alcohol-related brain damage: application to thiamine deficiency and cytokines<br><br>Section 11: Parkinson’s Disease 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine( MPTP)-induced mouse model of Parkinson's disease: impact of Valeriana officinalis<br>27. alpha-synuclein BAC transgenic mice model of Parkinson's disease: the sublaterodorsal tegmental nucleus and beyond<br>28. Rat model of parkinsonism: the nigro-vagal pathway<br><br>Section 12: Peripheral Neuropathy Non-mammalian animal models of peripheral neuropathy<br>29. Mouse models of peripheral neuropathy: neurogenic molecule NSI-189<br>30. Rat model of cisplatin-induced peripheral neuropathy: features and applications<br><br>Section 13: Prenatal Related Injury Porcine model of intrauterine growth restriction: Applications to the study of the hippocampus<br>31. Ethanol as a neurotoxin in model primates for in vitro exposure: brain development and beyond<br>32. Prenatal malnutrition: linking in oxidative stress<br><br>Section 14: Stroke Mouse model of ischemic stroke: PET tracers<br>33. Canine model of stroke: optimizing complex multimodal treatment<br>34. Porcine Ischemic Stroke and applications to neural stem cells