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Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside

Specificaties
Gebonden, blz. | Engels
Elsevier Health Sciences | e druk, 2021
ISBN13: 9780323757454
Rubricering
Elsevier Health Sciences e druk, 2021 9780323757454
€ 300,99
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Samenvatting

**Selected for Doody’s Core Titles® 2024 in Cardiology**

Fully updated from cover to cover, Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need—from new knowledge in basic science to the latest clinical advances in the field. Drs. José Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology.Packs each chapter with the latest information necessary for optimal basic research as well as patient careCovers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devicesContains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy, cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablationIncludes 47 new chapters covering both basic science and clinical topicsDiscusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection managementFeatures 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos onlineRecipient of a 2018 Highly Commended award from the British Medical AssociationEnhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

Specificaties

ISBN13:9780323757454
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

Section 1 STRUCTURAL AND MOLECULAR BASES OF ION CHANNEL FUNCTION<br>1. Voltage-gated sodium channels and electrical excitability of the heart<br>2. Voltage-gated calcium<br>3. Voltage-gated potassium channels<br>4. Structural and molecular bases of cardiac inward rectifier potassium channel function<br>5. Mammalian calcium pumps in health and disease<br>6. Structural and molecular bases of sarcoplasmic reticulum ion channel function<br>7. Organellar ion channels and transporters<br>8. Molecular organization, gating, and function of connexin-based gap junction channels and hemichannels<br><br>Section 2 BIOPHYSICS OF CARDIAC ION CHANNEL FUNCTION<br>9. Structure-function relations of heterotrimetric complexes of sodium channel a and β subunits<br>10. Regulation of cardiac calcium channels<br>11. Inhibition of phosphoinositide 3-kinase and acquired long QT syndrome<br>12. Structural determinants and biophysical properties of hERG1 channel gating<br>13. Molecular regulation of cardiac inward rectifier potassium channels by pharmacologic agents<br>14. Cardiac stretch-activated channels and mechano-electric coupling<br>15. Biophysical properties of gap junctions<br>16. Excitation-contraction coupling<br><br>Section 3 INTERMOLECULAR INTERACTIONS AND CARDIOMYOCYTE ELECTRICAL FUNCTION<br>17. Ion channel trafficking in the heart<br>18. Microdomain interactions of macromolecular complexes and regulation of the sodium channel nav1.5<br>19. Fibroblast growth factor homologous factors modulate cardiac calcium channels<br>20. Macromolecular complexes and cardiac potassium channels<br>21. Reciprocity of cardiac sodium and potassium channels in the control of excitability and arrhythmias<br>22. The intercalated disc: A molecular network that integrates electrical coupling, intercellular adhesion and cell excitability<br>23. Function and dysfunction of ion channel membrane trafficking and post translational modification<br>24. Feedback mechanisms for cardiac-specific microRNAs and cAMP signaling in electrical remodeling<br><br>Section 4 CELL BIOLOGY OF CARDIAC IMPULSE INITIATION AND PROPAGATION<br>25. Stem cell-derived nodal-like cardiomyocytes as a novel pharmacologic tool: Insights from sinoatrial node development and function<br>26. Gene therapy and biologic pacing<br>27. Intercellular communication and impulse propagation<br>28. Mechanisms of normal and dysfunctional sinoatrial nodal excitability and propagation<br>29. Cell biology of the specialized cardiac conduction system<br>30. Cardiac remodeling and regeneration<br><br>Section 5 MODELS OF CARDIAC EXCITATION<br>31. Ionic mechanisms of atrial action potentials<br>32. Genetic algorithms to generate dynamical complexity electrophysiological models<br>33. Calcium signaling in cardiomyocyte dodels with realistic geometries<br>34. Theory of rotors and arrhythmias<br>35. Computational approaches for accurate rotor localization in the human atria<br>36. Modeling the aging heart<br><br>Section 6 NEURAL CONTROL OF CARDIAC ELECTRICAL ACTIVITY<br>37. Innervation of the sinoatrial node<br>38. Mechanism for altered autonomic and oxidant regulation of cardiac sodium currents.<br>39. Pulmonary vein ganglia and the neural regulation of the heart rate<br>40. Neural activity and atrial tachyarrhythmias<br>41. Sympathetic innervation and cardiac arrhythmias<br><br>Section 7 ARRHYTHMIA MECHANISMS<br>42. The molecular pathophysiology of atrial fibrillation<br>43. Myofibroblasts, cytokines, and persistent atrial fibrillation<br>44. Role of the autonomic nervous system in atrial fibrillation<br>45. Rotors in human atrial fibrillation<br>46. Body surface frequency-phase mapping of atrial fibrillation<br>47. Panoramic mapping of atrial fibrillation from the body surface<br>48. Mechanisms of human ventricular tachycardia and human ventricular fibrillation<br>49. Genetics of atrial fibrillation<br><br>Section 8 MOLECULAR GENETICS AND PHARMACOGENOMICS<br>50. Mechanisms in heritable sodium channel diseases<br>51. Genetic, ionic, and cellular mechanisms underlying the J-wave syndromes<br>52. Inheritable potassium channel diseases<br>53. Inheritable phenotypes associated with altered intracellular calcium regulation<br><br>Section 9 PHARMACOLOGIC, GENETIC, AND CELL THERAPY OF ION CHANNEL DYSFUNCTION<br>54. Pharmacologic bases of antiarrhythmic therapy<br>55. Pharmacogenomics of cardiac arrhythmias<br>56. Gene therapy to treat cardiac arrhythmias<br>57. Highly mature human iPSC-derived cardiomyocytes as models for cardiac electrophysiology and drug testing<br>58. Cardiac repair with human induced pluripotent stem cell-derived cardiovascular cells.<br><br>Section 10 DIAGNOSTIC EVALUATION<br>59. Assessment of the patient with a cardiac arrhythmia<br>60. Electrocardiography of tachyarrhythmias: Differential diagnosis of narrow and wide QRS complex tachycardias<br>61. Electroanatomic mapping for arrhythmias<br>62. Computed tomography for electrophysiology<br>63. Magnetic resonance imaging for electrophysiology<br>64. Intracardiac echocardiography for electrophysiology<br>65. Exercise-induced arrhythmias<br>66. Cardiac monitoring: short- and long-term recording<br>67. Head-up tilt table testing<br>68. Autonomic regulation and cardiac risk<br>69. T-wave alternans<br>70. Noninvasive electrocardiographic imaging of human ventricular arrhythmias and Electrophysiological Substrate<br>71. Genetic testing<br><br>Section 11 SUPRAVENTRICULAR TACHYARRHYTHIAS: MECHANISMS, CLINICAL FEATURES, AND MANAGEMENT<br>72. Sinus node abnormalities<br>73. Atrial tachycardia<br>74. Atrial tachycardia in adults with congenital heart disease<br>75. Typical and atypical atrial flutter: Mapping and ablation<br>76. Atrial fibrillation<br>77. Preexcitation, atrioventricular reentry, variants<br>78. Electrophysiological characteristics of atrioventricular nodal reentrant tachycardia: Implications for the rentrant circuits<br>79. Junctional tachycardia<br><br>Section 12 VENTRICULAR TACHYCARRHYTHMIAS: MECHANISMS, CLNICAL FEATURES, AND MANAGEMENT<br>80. Premature ventricular complexes<br>81. Outflow tract ventricular tachycardias: Mechanisms, clinical features, and management<br>82. Fascicular ventricular arrhythmias<br>83. Bundle branch reentry tachycardia<br>84. Ischemic heart disease<br>85. Ventricular tachycardia in patients with dilated cardiomyopathy<br>86. Ventricular arrhythmias in hypertrophic cardiomyopathy<br>87. Ventricular tachycardias in arrhythmogenic right ventricular dysplasia/cardiomyopathy<br>88. VTs in catcholaminergic cardiomyopathy (catecholaminergic polymorphic ventricular tachycardia)<br>89. Ventricular arrhythmias in heart failure<br>90. Arrhythmias and conduction disturbances in non-compaction cardiomyopathy<br>91. Takotsubo cardiomyopathy<br>92. Brugada syndrome<br>93. Long and short QT syndromes<br>94. Anderson-Tawil syndrome<br>95. Timothy syndrome<br>96. J-wave syndromes<br>97. Idiopathic ventricular fibrillation<br>98. Sudden infant death syndrome<br>99. Sudden cardiac arrest/death in adults<br>100. Neurologic disorders<br>101. Drug-induced ventricular tachycardia<br>102. Ventricular arrhythmias in congenital heart disease<br><br>Section 13 SYNCOPE AND BRADYARRHYTHMIAS<br>103. Syncope<br>104. Postural orthostatic tachycardia syndrome<br>105. Progressive conduction system disease<br>106. Atrioventricular block<br><br>Section 14 ARRHYTHMIAS IN SPECIAL POPULATIONS PHARMACOLOGIC THERAPY<br>107. Sex differences in arrhythmias<br>108. Sudden cardiac death in athletes, including commotio cordis<br>109. Pediatric populations<br>110. Sleep-disordered breathing and arrhythmias<br>111. Ventricular assist devices and cardiac transplantation recipients<br><br>Section 15 PHARMACOLOGIC THERAPY<br>112. Standard antiarrhythmic drugs<br>113. Innovations in antiarrhythmic drug therapy<br>114. Nontraditional drugs for sudden cardiac death<br>115. Prevention of stroke in atrial fibrillation: warfarin, anti-factor Xa and thrombin drugs<br><br>Section 16 CARDIAC IMPLANTABLE ELECTRONIC DEVICES<br>116. Implantable cardioverter defibrillators: technical aspects<br>117. Implantable cardioverter defibrillators: clinical aspects<br>118. Subcutaneous implantable defibrillator<br>119. Implantable pacemakers<br>120. Cardiac resynchronization therapy<br>121. Newer applications of pacemakers<br>122. Remote monitoring<br><br>Section 17 CATHETER ABLATION<br>123. Catheter ablation: Technical aspects<br>124. Catheter ablation: Clinical aspects<br>125. Ablation for atrial fibrillation<br>126. Ablation of supraventricular tachycardias<br>127. Catheter ablation for ventricular tachycardias with/without structural heart disease<br>128. Epicardial and other approaches<br>129. Ventricular fibrillation<br>130. Ablation in pediatrics<br>131. Congenital heart disease<br>132. Anesthesiology for EP procedures<br><br>Section 18: SURGERY FOR ARRHYTHMIAS<br>133. Surgery for atrial fibrillation and other supraventricular tachycardias<br>134. Surgery for ventricular tachycardia<br><br>Section 19 NEW APPROACHES<br>135. Cervical vagal stimulation for heart failure<br>136. Baroreflex stimulation<br>137. Spinal cord stimulation for heart failure and arrhythmias<br>138. Renal artery denervation<br>139. Left atrial appendage occlusion/ligation
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        Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside