Section I: The liver and liver diseases<br>1. Prevalence of liver disease around the world<br>Helena Cortez-Pinto, Ana Craciun, Ricardo Crespo and Sofia Carvalhana<br>2. Viral hepatitis<br>Jean-Charles Duclos-Vallee<br>3. Non-alcoholic steatohepatitis<br>Miguel Pinheiro, Marta B. Afonso and Cecılia M.P. Rodrigues<br>4. Alcoholic liver disease<br>Zachary DeVore, Philip McNamara, Dimitri Belkin, Naveen Ganjoo and Deepika Devuni<br>5. Liver fibrosis and cirrhosis<br>Philipp Schwabl, Margarita Papatheodoridi and Massimo Pinzani<br>6. Biomarkers in liver disease and transplantation: Outlook for precision medicine<br>Ruslan A. Mammadov, Vincent T. Janmaat, Cornelia J. Verhoeven, Jan N.M. IJzermans,<br>Maikel P. Peppelenbosch, Luc J.W. van der Laan and Henk P. Roest<br>Section II: Liver transplantation<br>7. Living donor liver transplantation<br>Han Li, Paulo Martins, Babak Mavahedi and Adel Bozorgzadeh<br>8. Small-for-size syndrome in liver transplantation<br>Martin Montenovo<br>9. Clinical trials design and endpoints in liver transplantation<br>Richard W. Laing, Amanda P.C.S. Boteon and Yuri L. Boteon<br>10. Oncologic liver transplantation: Transplant oncology<br>Taizo Hibi<br>11. Management of hepatocellular carcinoma<br>Alejandro Serrablo, Alejandra Utrillas-Fornals, Pablo Parra, Luis Tejedor and Leyre Serrablo<br>Section III: Cell transplantation<br>12. Human hepatocyte transplantation<br>Jessica Nulty, Hanish Anand and Anil Dhawan<br>13. Mesenchymal stem cell transplantation<br>M. Najimi, G. de Bodt, G. Jannone and E.M. Sokal<br>14. Biliary tree stem cell transplantation<br>Savino Paradiso, Federica Cremisini, Matteo Franchitto, Guido Carpino and Vincenzo Cardinale<br>Section IV: Liver preservation and machine perfusion<br>15. General principles of organ preservation in liver transplantation<br>S.H. Abbas, F. Dengu and P.J. Friend<br>16. Ischemia-reperfusion injury<br>Joan Rosello Catafau and Arnau Panisello Rosello<br>Section V: Regenerative medicine in liver disease and transplantation<br>17. Liver regeneration<br>Udayan Apte<br>18. Whole-liver bioengineering: The future of transplantation medicine<br>Diogo Marques, Natalia Sanchez Romero, Sandra Meliton Barbancho, Alvaro Blanes Rodriguez, Pilar Sainz de la Masa Arnal, Helen Almeida, Pablo Royo Dachary and Pedro M. Baptista<br>19. Nanotechnology application in liver transplantation<br>Christine G. Yao<br>20. Acute liver failure and bioreactors/liver assist devices<br>Manon Guillet, Claire de Lartigue, Ulysse Pereira, Marwa Hussein, Mattia Pasqua and Cecile Legallais<br>21. Hepatobiliary organoids and large-scale expansion for regenerative therapies<br>Kerstin Schneeberger, Sara Morini and Bart Spee<br>22. Liver aging<br>Eric Felli and Jordi Gracia-Sancho