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Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Specificaties
Paperback, blz. | Engels
Elsevier Science | e druk, 2020
ISBN13: 9780128175927
Rubricering
Elsevier Science e druk, 2020 9780128175927
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue.

After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6.

Specificaties

ISBN13:9780128175927
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>Part 1: Green Chemistry<br></p> <p>Green Chemistry Assisted Synthesis of Natural and Synthetic Compounds as Anticancer Agents</p> <p>Antibacterial and Antimicrobial Coatings on Metal Substrate by Cold Spray Technique: Present and Future Perspectives </p> <p>Graphene Oxide Nanosheets as Sustainable Carbocatalysts: Synthesis of Medicinally Important Heterocycles </p> <p>Sustainable and Green Technologies for Synthesis of Potential Drugs Targeted Towards Tropical Diseases</p> <p>Clay-Mediated Synthesis of Biologically Active Molecules: Green and Sustainable Approaches </p> <p>The Role of Ionic Liquid in Medicinal Chemistry</p> <p>Synthesis of Medicinally Important Heterocycles Inside the Nanoreactors Built in Non-conventional Reaction Media </p> <p>Green Synthesis of Nanoparticles and Nanocomposites: Medicinal Aspects</p> <p>Part 2: Methods and Synthesis<br></p> <p>Use of Sustainable Organic Transformations in the Construction of Heterocyclic Scaffolds</p> <p>One-Pot Synthesis of Medicinally Active Compounds </p> <p>Organocatalytic Cycloaddition Reaction: A Gateway for Molecular Complexity</p> <p>Diverse Synthesis of Steroids </p> <p>Reactions in Water: Synthesis of Biologically Active Compounds</p> <p>Solventless Reactions: Green and Sustainable Approaches in Medicinal Chemistry</p> <p>Thiosugars in the Synthesis of Biologically Active Compounds </p> <p>Part 3: Medicinal Chemistry<br></p> <p>Implementing Green Chemistry for Synthesis of Cholesterol Lowering Statin Drugs</p> <p>Sustainable Release of Nanodrugs: A New Biosafe Approach </p> <p>Stimuli Responsive Sugar-Derived Hydrogels: A Modern Approach in Cancer Biology</p> <p>Green Synthesis and Biological Evaluation of Anticancer Drugs</p> <p>Green Chemistry and Synthetic Approaches in the Development of Antidepressant and Antipsychotic agents</p> <p>Part 4: Natural Products <br><br>Natural Spices in Medicinal Chemistry: Properties and Benefits</p> <p>Medicinal Plants and Their Compounds With Anticancer Properties<br></p> <p>Part 5: Microwave-Induced Chemistry <br></p> <p>Microwave-Assisted Synthesis of Anti-tubercular Agents: A Novel Approach</p> <p>Microwave-Induced Synthesis of Steroids and Their Chemical Manipulations</p> <p>Microwave-Induced Synthesis as a Part of Green Chemistry Approach for Novel Anti-inflammatory agents</p> <p>Part 6: Computers in Drug Discovery<br></p> <p>Dipole Moment of Medicinally Active Compounds: A Sustainable Approach</p> <p>Computational Methods and Tools for Sustainable and Green Approaches in Drug Discovery</p>

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        Green Approaches in Medicinal Chemistry for Sustainable Drug Design