Dosage Form Design Considerations

1. Preformulation in drug research and pharmaceutical product development<br>2. Physicochemical aspects to be considered in Pharmaceutical Product Development<br>3. Role of physicochemical parameters on drug absorption and their Implications in Pharmaceutical Product Development <br>4. Physiologic Factors Related to Drug Absorption<br>5. Physico-chemical, pharmaceutical and biological considerations in GIT Absorption of drugs<br>6. Influence of Drug Properties and Routes of Drug Administration on the design of controlled release systems<br>7. Drug stability and degradation studies<br>8. First pass metabolism considerations in Pharmaceutical Product Development<br>9. Dissolution profile considerations during Pharmaceutical Product Development<br>10. Drug disposition considerations in Pharmaceutical Product Development<br>11. Protein and tissue binding: Implication on pharmacokinetic parameters <br>12. Preformulation studies of drug substances, proteins and peptides: Role in drug discovery and Pharmaceutical Product Development<br>13. Role of salt selection in drug discovery and development<br>14. Drug Complexation: Implications in drug solubilization and oral bioavailability enhancement<br>15. Solubility and solubilization approaches in Pharmaceutical Product Development<br>16. Rheology and its implications on performance of liquid dosage forms<br>17. Micromeritics in Pharmaceutical Product Development<br>18. Four stages in Pharmaceutical Product Development – Preformulation – Prototype development - Biological aspects - Scale up studies – Commercialization  <br>19. Scale up studies in Pharmaceutical Product Development<br>20. Manipulation of physiological processes for Pharmaceutical Product Development<br>21. Impact of pharmaceutical product Quality on Clinical Efficacy<br>22. Formulation additives used in Pharmaceutical Products: Emphasis on regulatory perspectives and GRAS