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Pharmacoepigenetics

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2019
ISBN13: 9780128139394
Rubricering
Elsevier Science e druk, 2019 9780128139394
Onderdeel van serie Translational Epigenetics
€ 211,00
Levertijd ongeveer 8 werkdagen

Samenvatting

Pharmacoepigenetics provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development.

Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.

Specificaties

ISBN13:9780128139394
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1. The Epigenetic Machinery in the Life Cycle and Pharmacoepigenetics<br>2. Pharmacoepigenetics: Basic Principles for Personalized Medicine<br>3. Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport<br>4. MicroRNA-Dependent Gene Regulation of the Human Cytochromes P450<br>5. Pathoepigenetics: The Role of Epigenetic Biomarkers in Disease Pathogenesis<br>6. Pharmacoepigenetic Processors: Epigenetic Drugs, Drug Resistance, Toxicoepigenetics, and Nutriepigenetics<br>7. Pharmacoepigenetics of Novel Nucleoside DNA Methyltransferase Inhibitors<br>8. Pharmacoepigenetics: Novel Mechanistic Insights in Drug Discovery and Development Targeting Chromatin-Modifying Enzymes<br>9. Pharmacoepigenetics of EZH2 Inhibitors<br>10. Regulators of Histone Acetylation: Bromodomain Inhibitors<br>11. Bromodomain Inhibition and Its Application to Human Disease<br>12. Epigenetic Drug Discovery for Cancer<br>13. Pharmacoepigenetics of Histone Deacetylase Inhibitors in Cancer<br>14. Pharmacoepigenetics of LSD1 Inhibitors in Cancer<br>15. Pharmacoepigenetic Considerations for the Treatment of Breast Cancer<br>16. Pharmacoepigenetics of Acute Myeloid Leukemia<br>17. Therapeutic Potential of Pharmacoepigenetics in Cholangiocarcinoma<br>18. Pharmacoepigenetics in Type 2 Diabetes Mellitus<br>19. Pharmacoepigenetics of Immunological Disorders<br>20. Pharmacoepigenetics of Rheumatic Disorders<br>21. Pharmacoepigenetics of Systemic Lupus Erythematosus<br>22. Epigenetics and Pharmacoepigenetics of Neurodevelopmental and Neuropsychiatric Disorders<br>23. Pharmacoepigenetics and Toxicoepigenetics in Neurodevelopmental Disorders<br>24. Pharmacoepigenetics of Autism Spectrum Disorder<br>25. Pharmacoepigenetics of Antipsychotic Drugs<br>26. Pharmacoepigenetics of Bipolar Disorder<br>27. Pharmacoepigenetics of Major Depression<br>28. Pharmacoepigenetics of Vertigo and Related Vestibular Syndromes<br>29. Pharmacological Nicotinamide: Mechanisms Centered Around SIRT1 Activity<br>30. Pharmacoepigenetics and Pharmacoepigenomics of Valproate in Neurodegenerative Disease<br>31. Pharmacoepigenetics of Statins<br>32. Pharmacoepigenetics of Memantine in Dementia<br>33. Epigenetics in Doxorubicin Cardiotoxicity<br>34. Pharmacoepigenetics of Brassica-Derived Compounds<br>35. Pharmacoepigenetics of Chinese Herbal Components in Cancer<br>36. Epigenetics of Aging and Age-Related Disorders<br>37. Epigenetics of Aging and Cancer: A Comprehensive Look<br>38. Epigenetics and Pharmacoepigenetics of Age-Related Neurodegenerative Disorders</p>
€ 211,00
Levertijd ongeveer 8 werkdagen

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        Pharmacoepigenetics