Phosphatases

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2018
ISBN13: 9780128138816
Rubricering
Elsevier Science e druk, 2018 9780128138816
Onderdeel van serie Methods in Enzymology
€ 178,50
Levertijd ongeveer 8 werkdagen

Samenvatting

Methods in Enzymology, Volume 607: Phosphatases, the latest release in this ongoing series, highlights new advances in the field as detailed by an international board of authors. This latest release includes chapters on Empirical Valence Bond Simulations of the Evolution of Enzyme Function, QM/MM Free Energy and Kinetic Isotope Analysis of Phosphoryl Transfer in Enzymes, the Structural, Mechanism and Evolution of Phosphatases, How to Define Rapid Motions in Pumping Pyrophosphatases, The Evolution of K+-Independence in Pyrophosphatases, the Crystallization of Michaelis, Intermediate and Inhibited Complexes in Phosphatases, and an Investigation of Nucleotide Loading and Effector Binding of K-Ras.

Specificaties

ISBN13:9780128138816
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1. Empirical Valence Bond Simulations of Organophosphate Hydrolysis: Theory and Practice<br>Miha Purg and Shina Caroline Lynn Kamerlin<br>2. Analysis of Phosphoryl-Transfer Enzymes With QM/MM Free Energy Simulations<br>Daniel Roston, Xiya Lu, Dong Fang, Darren Demapan and Qiang Cui<br>3. Defining Dynamics of Membrane-Bound Pyrophosphatases by Experimental and Computational Single-Molecule FRET<br>Steven P.D. Harborne, Jannik Strauss, Ainoleena Turku, Matthew A. Watson, Roman Tuma, Sarah A. Harris and Adrian Goldman<br>4. A Simple Strategy to Determine the Dependence of Membrane-Bound Pyrophosphatases on K<SUP>+</SUP> as a Cofactor<br>Jannik Strauss, Craig Wilkinson, Keni Vidilaseris, Steven P.D. Harborne and Adrian Goldman<br>5. Crystallization of Liganded Phosphatases in the HAD Superfamily <br>Christine Harvey, Katherine O’Toole and Karen N. Allen<br>6. Structure, Mechanism, and Substrate Profiles of the Trinuclear Metallophosphatases From the Amidohydrolase Superfamily<br>Swapnil V. Ghodge and Frank M. Raushel<br>7. Affinities and Comparisons of Enzyme States by Principal Component Analysis of NMR Spectra, Automated Using TREND Software<br>Jia Xu and Steven R. Van Doren<br>8. Assessment and Impacts of Phosphorylation on Protein Flexibility of the α-D-Phosphohexomutases<br>Kyle M. Stiers and Lesa J. Beamer<br>9. Chemical Tools for Studying the Impact of cis/trans Prolyl Isomerization on Signaling: A Case Study on RNA Polymerase II Phosphatase Activity and Specificity<br>Nathaniel Tate Burkholder, Brenda Medellin, Seema Irani, Wendy Matthews, Scott A. Showalter and Yan Jessie Zhang<br>10. Quantitative Analysis of Intracellular Response Regulator Phosphatase Activity of Histidine Kinases<br>Rong Gao and Ann M. Stock<br>11. Measuring the Activities of Two-Component Regulatory System Phosphatases<br>Robert B. Bourret and Ruth E. Silversmith<br>12. Assembly of PGAM5 Into Multimeric Complexes Provides a Mechanism for Allosteric Regulation of Phosphatase Activity<br>Peter Tipton, Tong Su and Mark Hannink<br>13. Purification of Lipin and Measurement of Phosphatidic Acid Phosphatase Activity From Liposomes<br>Mitchell E. Granade and Thurl E. Harris<br>14. Combining SAMDI Mass Spectrometry and Peptide Arrays to Profile Phosphatase Activities<br>Lindsey C. Szymczak, Che-Fan Huang, Eric J. Berns and Milan Mrksich<br>15. Protein Chemical Approaches to Understanding PTEN Lipid Phosphatase Regulation<br>Daniel R. Dempsey and Philip A. Cole</p>
€ 178,50
Levertijd ongeveer 8 werkdagen

Rubrieken

    Personen

      Trefwoorden

        Phosphatases