Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2018
ISBN13: 9780128127407
Rubricering
Elsevier Science e druk, 2018 9780128127407
Onderdeel van serie Methods in Enzymology
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Samenvatting

Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A, Volume 602 assembles new information on our understanding of anesthesia. This latest release in the series includes sections on how physical accuracy leads to biological relevance, best practices for simulating ligand-gated ion channels interacting with general anesthetics, computational approaches for studying voltage-gated ion channels modulation by general anesthetics, anesthetic parameterization, pharmacophore QSAR, QM, ONIOM, and kinetic modeling of electrophysiology data.

Specificaties

ISBN13:9780128127407
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>Computational approaches<br>1. Physical accuracy leads to biological relevance: Best practices for simulating ligand-gated ion channels interacting with general anesthetics<br>Grace Brannigan and Sruthi Murlidaran<br>2. Computational approaches for studying voltage-gated ion channels modulation by general anesthetics<br>Vincenzo Carnevale<br>3. Anesthetic parameterization<br>Jerome Henin<br>4. Pharmacophore QSAR, QM, ONIOM<br>Edward Bertaccini<br>5. Kinetic modeling of electrophysiology data<br>Robert Cantor</p> <p>Genetics and model organisms<br>6. General genetic strategies<br>Philip G. Morgan<br>7. Worms<br>Margaret Sedensky<br>8. Flies<br>Bruno van Swinderen<br>9. Tadpoles<br>Kellie Ann Woll<br>10. Zebrafish<br>Victoria Bedell and Julia Dallman<br>11. Mice<br>Max Kelz</p> <p>Photolabeling<br>12. Mass spect ID of adducts<br>Kellie Ann Woll<br>13. Photolabeling protection/competition<br>Jonathan Cohen</p> <p>Xenon<br>14. Xenon-protein interactions<br>Benjamin Roose and Ivan Dmochowski<br>15. Xenon gas delivery/recovery procedures<br>Mervyn Maze<br>16. Hyperpolarized Xe-129 MRI<br>Mitchell Albert<br>17. CT imaging<br>Andrew McKinstry-Wu</p> <p>Electrophysiology<br>18. Native system electrophysiology (slices, cells, in vivo)<br>Boris Heifets<br>19. Voltage-gated ion channels (Kv, Nav)<br>Manuel Covarrubias and Elaine Yang<br>20. Ligand-gated ion channels<br>Stuart A. Forman</p>
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        Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A