<p>1. Molecular Modeling and Chemoinformatics to Advance the Development of Modulators of Epigenetic Targets: A Focus on DNA Methyltransferases<br>Fernando D. Prieto-Martínez, Andrea Peña-Castillo, Oscar Méndez-Lucio, Eli Fernández-De Gortari and José L. Medina-Franco<br>2. Recent Advances in Computational Models for the Study Protein-Peptide Interactions<br>Denise Kilburg and Emilio Gallicchio<br>3. Structural Plasticity in Globins: Role of Protein Dynamics in Defining Ligand Migration Pathways<br>C. Estarellas, L. Capece, C. Seira, A. Bidon-Chanal, D. A. Estrin and F. J. Luque<br>4. Dynamic Reorganization and Enzymatic Remodeling of Type IV Collagen at Cell- Biomaterial Interface<br>Nuno Miranda Coelho, Virginia Llopis-Hernández, Manuel Salmerón-Sánchez and George Altankov<br>5. Cytochromes P450: History, Classes, Catalytic Mechanism and Industrial Application<br>Darren J. Cook, James D. Cook, Ken Cook, Gary W. Black and Simon J. Charnock<br>6. Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A<br>Laura J. Kay, Tora K. Smulders-Srinivasan and Meera Soundararajan<br></p>