1. Isothermal Titration Calorimetry Measurements of Metal Ions Binding to Proteins<br>Colette F. Quinn ,Margaret C. Carpenter, Molly L. Croteau and Dean E. Wilcox<br>2. Assessing Coupled Protein Folding and Binding through Temperature- Dependent Isothermal Titration Calorimetry<br>Debashish Sahu, Monique Bastidas, Chad W. Lawrence, William G. Noid,and Scott A. Showalter<br>3. Fragment-Based Screening for Enzyme Inhibitors Using Calorimetry<br>Michael I. Recht, Vicki Nienaber and Francisco E. Torres<br>4. Measuring Multivalent Binding Interactions by Isothermal Titration Calorimetry<br>Tarun K. Dam, Melanie L Talaga, Ni Fan and Curtis F. Brewer<br>5. Calorimetric and Spectroscopic Analysis of the Thermal Stability of Short Duplex DNA-Containing Sugar and Base-Modified Nucleotides<br>Kareem Fakhfakh, Curtis B. Hughesman, A. Louise Creagh, Vincent Kao and Charles Haynes<br>6. Calorimetric Quantification of Cyclodextrin-Mediated Detergent Extraction for Membrane-Protein Reconstitution<br>Martin Textor and Sandro Keller<br>7. Extending ITC to Kinetics with KinITC<br>Philippe Dumas, Eric Ennifar, Cyrielle Da Veiga, Guillaume Bec, William Palau, Carmelo Di Primo,Angel Piñeiro, Juan Sabin, Eva Muñoz and Javier Rial<br>8. Measuring the Kinetics of Molecular Association by Isothermal Titration Calorimetry <br>Kirk A. Vander Meulen, Scott Horowitz, Raymond C. Trievel, and Samuel E. Butcher<br>9. Isothermal Titration Calorimetry to Characterize Enzymatic Reactions<br>Luca Mazzei, Stefano Ciurli and Barbara Zambelli<br>10. Avoiding Buffer Interference in Itc Experiments: A Case Study from the Analysis of Entropy Driven Reactions of Glucose-6-Phosphate Dehydrogenase<br>M. Lucia Bianconi<br>11. ITC Methods for Assessing Buffer/Protein Interactions from the Perturbation of Steady-State Kinetics: A Reactivity Study of Homoprotocatechuate 2,3-Dioxygenase<br>Kate L. Henderson, Delta K. Boyles, Vu H. Le, Edwin A. Lewis and Joseph P.Emerson<br>12. Modern Analysis of Protein Folding by Differential Scanning Calorimetry<br>Beatriz Ibarra-Molero, Athi N. Naganathan, Jose M. Sanchez-Ruiz and Victor Muñoz<br>13. A Guide to Differential Scanning Calorimetry of Membrane and Soluble Proteins in Detergents<br>Zhengrong Yang and Christie G. Brouillette<br>14. Orthogonal Methods for Characterizing the Unfolding of Therapeutic Monoclonal Antibodies: Differential Scanning Calorimetry, Isothermal Chemical Denaturation and Intrinsic Fluorescence with Concomitant Static Light Scattering<br>Deniz B. Temel, Pavel Landsman and Mark L. Brader<br>15. IATC, DSC, and PPC Analysis of Reversible and Multi-State Structural Transition of Cytochrome c<br>Shun-ichi Kidokoro and Shigeyoshi Nakamura<br>16. The Complementarity of the Loop to the Stem in DNA Pseudoknots Gives Rise to Local TAT Base-Triplets<br>Calliste Reiling-Steffensmeier and Luis A. Marky<br>17. A High-Throughput Biological Calorimetry Core: Steps to Startup, Run, and Maintain a Multi-User Facility<br>Neela H. Yennawar, Julia A. Fecko, Scott A. Showalter and Philip C. Bevilacqua