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Translating Gene Therapy to the Clinic

Techniques and Approaches

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2014
ISBN13: 9780128005637
Rubricering
Elsevier Science e druk, 2014 9780128005637
€ 128,20
Levertijd ongeveer 8 werkdagen

Samenvatting

Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research. It emphasizes methods, tools, and experimental approaches used by leaders in the field of translational gene therapy. The book promotes cross-disciplinary communication between the sub-specialties of medicine, and remains unified in theme.

Specificaties

ISBN13:9780128005637
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

1. Introduction <br>2. Translating genome engineering to better clinical outcomes <br>3. Arthritis Gene Therapy and Its Tortuous Path into the Clinic<br>4. Mechanistic Basis of Immunotherapies for Type 1 Diabetes Mellitus <br>5. Gene therapy for retinal disease <br>6. Gene Therapy in Cystic Fibrosis <br>7. Evaluating Risks of Insertional Mutagenesis by DNA Transposons in Gene Therapy <br>8. Pluripotent Stem Cells and Gene Therapy <br>9. Gene therapy for hemoglobinopathies: progress and challenge <br>10. Hemophilia Clinical Gene Therapy-brief review <br>11. Gene Transfer for Congestive Heart Failure<br>12. Gene therapy for the prevention of vein graft disease <br>13. Current status of gene therapy for brain tumors <br>14. Oncolytic virus therapy for cancer: The first wave of translational clinical trials <br>15. T-Cell Gene Therapy <br>16. Immune responses to gene therapy
€ 128,20
Levertijd ongeveer 8 werkdagen

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        Translating Gene Therapy to the Clinic