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Osteogenesis Imperfecta

A Translational Approach to Brittle Bone Disease

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2013
ISBN13: 9780123971654
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Elsevier Science e druk, 2013 9780123971654
€ 235,00
Levertijd ongeveer 8 werkdagen

Samenvatting

Osteogenesis Imperfecta is the first translational reference professionals can turn to for a source of comprehensive information on this disorder. Although several reviews of the field have been published in various journals, there is no other single source for a compendium of current information. Separate chapters discuss each of the several clinical features of OI. Ethical issues related to OI are discussed, as is the importance of nutrition in managing the OI child and the OI adult. The role of physical medicine and rehabilitation for OI patients is also presented, along with the current status of OI medical treatment and the prospects for genetic engineering in the future. The text also provides the orthopedic surgeon with an advanced discussion of surgical techniques applicable to OI.

Specificaties

ISBN13:9780123971654
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

Foreword <br>Acknowledgments <br>List of Contributors <br>Section 1: INTRODUCTION <br>Section 2: BONE BIOLOGY, STRUCTURE AND BIOCHEMISTRY <br>Section 3: CLINICAL AND MOLECULAR GENETICS OF OSTEOGENESIS IMPERFECTA <br>Section 4: COL1A1 AND COL1A2 MUTATIONS <br>Section 5: ANIMAL MODELS OF OSTEOGENESIS IMPERFECTA <br>Section 6: BRITTLE BONE OVERLAP PHENOTYPES: TGF-BETA MUTATIONS AND BONE <br>Section 7: CLINICAL ASPECTS OF OSTEOGENESIS IMPERFECTA <br>Section 8: ORGAN INVOLVEMENT IN OSTEOGENESIS IMPERFECTA <br>Chapter 9: ORTHOPEDICS <br>Section 10: PHYSICAL MEDICINE AND REHABILITATION <br>Section 11: PHARMACOLOGIC TREATMENT OF OSTEOGENESIS IMPERFECTA <br>Section 12: GENETIC APPROACH TO TREATMENT OF OSTEOGENESIS IMPERFECTA <br>Index
€ 235,00
Levertijd ongeveer 8 werkdagen

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        Osteogenesis Imperfecta