Natural Product Biosynthesis by Microorganisms and Plants Part B

<ol> <li>In vivo production of thiopeptide variants</li> <li>Microviridin biosynthesis</li> <li>Cyclotide isolation and characterization</li> <li>Ribosomally-encoded cyclic peptide toxins from mushrooms</li> <li>The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: novel function for a non-ribosomal peptide synthetase</li> <li>Discovery and biosynthesis of phosphonate and phosphinate natural products</li> <li>RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins </li> <li>Fe(II)-dependent, uridine-5’-monophosphate α-ketoglutarate dioxygenases in the synthesis of 5’-modified nucleosides</li> <li>Heme-dependent Tailoring Enzymes in Natural Product Biosynthesis: Spectroscopic Characterisation of the L-tryptophan-nitrating Cytochrome P450 TxtE</li> <li>Oxidative Tailoring Reactions Catalysed by Non-heme Iron-dependent Enzymes: Streptorubin B Biosynthesis as an Example</li> <li>The rare fluorinated natural products and biotechnological prospects for fluorine enzymology</li> <li>Enzymatic chlorination and bromination</li> <li>Prenyltransferases of the dimethylallyltryptophan synthase superfamily</li> <li>Serine carboxypeptidase-like acyltransferases from plants</li> <li>4-Methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis</li> <li>Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis</li> <li>High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer<br><br></li></ol>