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Biology of Serpins

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2011
ISBN13: 9780123864710
Rubricering
Elsevier Science e druk, 2011 9780123864710
Onderdeel van serie Methods in Enzymology
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.

Specificaties

ISBN13:9780123864710
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<ol> <li>Analysis of Serpin Secretion, Misfolding and Surveilance in the Endoplasmic Reticulum</li> <p>Shujuan Pan, Michael J. Iannotti and Richard N. Sifers</p> <p> <li>Serpin-Enzyme Receptors: Ldl Receptor Related Protein 1</li> <p>Dudley K. Strickland, Selen Catania Muratoglu<SUP> </SUP>and Toni M. Antalis</p> <p> <li>The Role of Autophagy in Alpha-1-Antitrypsin Deficiency</li> <p>Tunda Hidvegi, Amitava Mukherjee, Michael Ewing, Carolyn Kemp and David H. Perlmutter</p> <p> <li>Serpins and the Complement System</li> <p>László Beinrohr, Thomas A. Murray-Rust, Leanne Dyksterhuis, Péter Závodszky, Péter Gál, Robert N. Pike and Lakshmi C. Wijeyewickrema</p> <p> <li>Use of Mouse Models to Study Plasminogen Activator Inhibitor-1</li> <p>Paul J. Declerck, Ann Gils<SUP> </SUP>and Bart De Taeye</p> <p> <li>Plasminogen Activator Inhibitor Type 2: Still An Enigmatic Serpin But A Model For Gene Regulation</li> <p>Robert L. Medcalf</p> <p> <li>The Serpinb1 Knock-Out Mouse: A Model For Studying Neutrophil Protease Regulation in Homeostasis and Inflammation</li> <p>Charaf Benarafa</p> <p> <li>Investigating Maspin in Breast Cancer Progression Using Mouse Models</li> <p>Michael P. Endsley and Ming Zhang</p> <p> <li>Hsp47as A Collagen-Specific Molecular Chaperone</li> <p>Yoshihito Ishida and Kazuhiro Nagata</p> <p> <li>Assays for the Antiangiogenic and Neurotrophic Serpin Pigment Epithelium‐Derived Factor</li> <p>S. Patricia Becerra, Susan E. Crawford and Preeti Subramanian</p> <p> <li>The Drosophila Serpins: Multiple Functions in Immunity and Morphogenesis</li> <p>Jean Marc Reichhart, David Gubb<SUP> </SUP>and Vincent Leclerc</p> <p> <li>Modelling Serpin Conformational Diseases in Drosophila Melanogaster</li> <p>Thomas R. Jahn, Elke Malzer, John Roote, Anastasia Vishnivetskaya, Sara Imarisio, Maria Giannakou, Karin Panser, Stefan Marciniak, Damian C. Crowther</p> <p> <li>Using Caenorhabditis Elegans to Study Serpinopathies</li> <p>Olivia S. Long, Sager J. Gosai, Joon Hyeok Kwak, Dale E. King, David H. Perlmutter, Gary A. Silverman and Stephen C. Pak</p> <p> <li>Using c. Elegans to Identify the Protease Targets of Serpins In Vivo.</li> <p>Sangeeta R. Bhatia, Mark T. Miedel, Cavita K. Chotoo, Nathan J. Graf, Brian L. Hood, Thomas P. Conrads, Gary A. Silverman and Cliff J. Luke</p> <p> <li>Viral Serpin Therapeutics: From Concept to Clinic</li> <p>Hao Chen, MD, PhD, Donghang Zheng, MD, PhD, Jennifer Davids, BA, Mee Yong Bartee, PhD, Erbin Dai, MD, Liying Liu, MD, Lyubomir Petrov, MD, PhD, Colin Macaulay, PhD, Robert Thoburn, MD, Eric Sobel, MD, PhD, Richard Moyer, PhD, Grant McFadden, PhD, Alexandra Lucas, MD, FRCP(C)</p> <p> <li>Human Scca Serpins Inhibit Staphylococcal Cysteine Proteases by Forming Classic "Serpin-Like" Covalent Complexes</li> <p>Tomasz Kantyka and Jan Potempa</p> <p> <li>Plants and the Study of Serpin Biology</li> </ol> <p>Thomas H. Roberts, Joon-Woo Ahn, Nardy Lampl and Robert Fluhr</p>

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