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Cilia: Model Organisms and Intraflagellar Transport

Specificaties
Gebonden, blz. | Engels
Elsevier Science | e druk, 2009
ISBN13: 9780123813770
Rubricering
Elsevier Science e druk, 2009 9780123813770
Onderdeel van serie Methods in Cell Biology
€ 172,25
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Samenvatting

Cilia are highly conserved organelles that serve motile functions, sensory functions, or both. These organelles power cell movement, generate fluid flow in various organs, act as sensors of the extracellular environment and have been modified for various specialized tasks such as light reception and smell. Defects in these ubiquitous organelles lead to a broad array of human genetic disorders that range from polycystic kidney disease, retinal degeneration, epilepsy and infertility to developmental defects such as situs inversus and polydactyly. This volume is the third in a three-part series on cilia that focuses on the use of model organisms to gain insight into ciliary function and on the process of intraflagellar transport that is essential for the assembly and maintenance of ciliary structures.

Specificaties

ISBN13:9780123813770
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1. Manipulating Ciliary Protein-Encoding Genes in Tetrahymena thermophila</p> <p>Drashti Dave, Dorota Wloga, and Jacek Gaertig</p> <p>2. Approaches for Functional Analysis of Flagellar Proteins in African Trypanosomes</p> <p>Michael Oberholzer, Miguel A. Lopez, Katherine S. Ralston, and Kent L. Hill</p> <p>3. Tools for Analyzing Intraflagellar Transport in Trypanosomes</p> <p>Daria Julkowska and Philippe Bastin</p> <p>4. Schmidtea mediterranea: A Model System for Analysis of Motile Cilia</p> <p>Panteleimon Rompolas, Ramila S. Patel-King, and Stephen M. King</p> <p>5. Targeted Gene Silencing by RNA Interference in Chlamydomonas</p> <p>Eun-Jeong Kim and Heriberto Cerutti</p> <p>6. Analysis of Cargo Transport by IFT and GFP Imaging of IFT in Chlamydomonas</p> <p>Dennis Diener</p> <p>7. Genetic and Phenotypic Analysis of Flagellar Assembly Mutants</p> <p>in Chlamydomonas reinhardtii</p> <p>Carlo Iomini, Jacob E. Till, and Susan K. Dutcher</p> <p>8. Recording and Analyzing IFT in Chlamydomonas Flagella</p> <p>William Dentler, Kristyn VanderWaal, and Mary E Porter</p> <p>9. Total Internal Reflection Fluorescence (TIRF) Microscopy</p> <p>of Chlamydomonas Flagella</p> <p>Benjamin D. Engel, Karl-Ferdinand Lechtreck, Tsuyoshi Sakai, Mitsuo Ikebe, George B. Witman, and</p> <p>Wallace F. Marshall</p> <p>10. Purification of IFT Particle Proteins and Preparation of Recombinant</p> <p>Proteins for Structural and Functional Analysis</p> <p>Robert H. Behal, Ewelina Betleja, and Douglas G. Cole</p> <p>11. Studying Cilia in Zebrafish</p> <p>Iain Drummond</p> <p>12. Analysis of IFT Kinesins in Developing Zebrafish Cone Photoreceptor</p> <p>Sensory Cilia</p> <p>Christine Insinna, Katherine Luby-Phelps, Brian A. Link, and Joseph C. Besharse</p> <p>13. Analysis of Intraflagellar Transport in C. elegans Sensory Cilia</p> <p>Limin Hao, Seyda Acar, James Evans, Guangshuo Ou, and Jonathan M. Scholey</p> <p>14. Functional Genomics of Intraflagellar Transport-Associated Proteins in C. elegans</p> <p>Peter N. Inglis, Oliver E. Blacque, and Michel R. Leroux</p> <p>15. Generating Conditional Mutants to Analyze Ciliary Functions:</p> <p>The Use of Cre–Lox Technology to Disrupt Cilia in Specific Organs</p> <p>Amber K. O’Connor, Robert A. Kesterson, and Bradley K. Yoder</p> <p>16. Imaging Intraflagellar Transport in Mammalian Primary Cilia</p> <p>Tatiana Y. Besschetnova, Barnali Roy, and Jagesh V. Shah</p> <p>17. Analysis of Hedgehog Signaling in Mouse Intraflagellar Transport Mutants</p> <p>Hyuk W. Ko, Aimin Liu, and Jonathan T. Eggenschwiler</p>
€ 172,25
Levertijd ongeveer 8 werkdagen

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        Cilia: Model Organisms and Intraflagellar Transport